HitPredict

Interactor 1: HDAC1 (Q13547)
Histone deacetylase 1 (HD1) (EC 3.5.1.98) (Protein deacetylase HDAC1) (EC 3.5.1.-) (Protein decrotonylase HDAC1) (EC 3.5.1.-)
Gene: HDAC1

Interactor 2: IFT74 (Q96LB3)
Intraflagellar transport protein 74 homolog (Capillary morphogenesis gene 1 protein) (CMG-1) (Coiled-coil domain-containing protein 2)
Gene: IFT74

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	34709266
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0045944 - positive regulation of transcription by RNA polymerase II
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 482 Hs			1 600
+	Hs
		1038450 HDAC1_HUMAN (1-482): 0: 668: 100.00		MRCKA_HUMAN (169-598): 7.2e-58: 212: 16.63
+	Hs
		1038371 HDAC1_HUMAN (1-482): 0: 668: 100.00		DCTN1_HUMAN (10-416): 1.26e-29: 127: 15.22
+	Hs
		724813 HDAC1_HUMAN (1-482): 0: 668: 100.00		MYH9_HUMAN (40-497): 4.47e-16: 84.3: 8.52
+	Hs
		522611 HDAC1_HUMAN (1-482): 0: 668: 100.00		MYH7_HUMAN (68-526): 5.93e-16: 83.9: 8.94
+	Hs
		724945 HDAC2_HUMAN (1-478): 0: 666: 85.92		MYH9_HUMAN (40-497): 4.47e-16: 84.3: 8.52
+	Hs
		1038808 HDAC1_HUMAN (1-482): 0: 668: 100.00		MYH2_HUMAN (210-600): 1.7e-14: 79.2: 8.91
+	Hs
		528410 HDAC1_HUMAN (1-482): 0: 668: 100.00		MYH8_HUMAN (215-600): 2.47e-14: 78.9: 8.88
+	Hs
		1038853 HDAC1_HUMAN (1-482): 0: 668: 100.00		MYH4_HUMAN (210-600): 2.11e-13: 75.8: 9.16
+	Hs
		522547 HDAC1_HUMAN (1-482): 0: 668: 100.00		MYH1_HUMAN (210-600): 2.88e-13: 75.4: 9.42
+	Hs
		148775 HDAC1_HUMAN (1-482): 0: 668: 100.00		CTRO_HUMAN (101-590): 8.63e-13: 73.9: 14.98
+	Hs
		149134 HDAC2_HUMAN (1-478): 0: 666: 85.92		CTRO_HUMAN (101-590): 8.63e-13: 73.9: 14.98
+	Hs
		1038680 HDAC1_HUMAN (1-482): 0: 668: 100.00		CP250_HUMAN (77-598): 5.84e-10: 64.6: 9.11
+	Hs
		725212 HDAC2_HUMAN (1-478): 0: 666: 85.92		MYH10_HUMAN (56-432): 6.11e-09: 61.5: 12.47
+	Sp
		140679 PHD1_SCHPO (7-415): 0: 524: 52.91		SPO15_SCHPO (38-592): 1.52e-41: 163: 19.38
+	Hs
		1051497 HDAC6_HUMAN (16-325): 2.05e-93: 309: 25.78		DCTN1_HUMAN (10-416): 1.26e-29: 127: 15.22
+	Mm
		1143175 HDAC6_MOUSE (11-325): 4.35e-103: 334: 25.69		MYH10_MOUSE (57-497): 8.28e-18: 90: 9.96
+	Hs
		728525 HDAC6_HUMAN (16-325): 2.05e-93: 309: 25.78		MYH11_HUMAN (52-534): 2.45e-16: 85.4: 11.72
+	Hs
		725053 HDAC6_HUMAN (16-325): 2.05e-93: 309: 25.78		MYH9_HUMAN (40-497): 4.47e-16: 84.3: 8.52
+	Hs
		551864 HDAC6_HUMAN (16-325): 2.05e-93: 309: 25.78		DESP_HUMAN (64-554): 2.32e-12: 72.4: 14.65
+	Hs
		725261 HDAC6_HUMAN (16-325): 2.05e-93: 309: 25.78		MYH10_HUMAN (56-432): 6.11e-09: 61.5: 12.47