Interactor 1: LCK (P06239)
Tyrosine-protein kinase Lck (EC 2.7.10.2) (Leukocyte C-terminal Src kinase) (LSK) (Lymphocyte cell-specific protein-tyrosine kinase) (Protein YT16) (Proto-oncogene Lck) (T cell-specific protein-tyrosine kinase) (p56-LCK)
Gene: LCK

Interactor 2: FERM2 (Q96AC1)
Fermitin family homolog 2 (Kindlin-2) (Mitogen-inducible gene 2 protein) (MIG-2) (Pleckstrin homology domain-containing family C member 1) (PH domain-containing family C member 1)
Gene: FERMT2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.38 1.00 0.618

The method score is based on:

Property Details
Experiments 34079125
Identification Methods proximity labelling technology
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains FERM_M~PK_Tyr_Ser-Thr, PH~PK_Tyr_Ser-Thr, PH~SH3_1
Common GO terms GO:0005829 - cytosol
GO:0005886 - plasma membrane
GO:0019901 - protein kinase binding
GO:0031234 - extrinsic component of cytoplasmic side of plasma membrane
Homologous interactions 4

Homologous interactions

Color coding for hit scores

1 509
Hs

1 680
+ Hs
+ Hs
+ Hs
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024