HitPredict

Interactor 1: LCK (P06240)
Proto-oncogene tyrosine-protein kinase LCK (EC 2.7.10.2) (Leukocyte C-terminal Src kinase) (LSK) (Lymphocyte cell-specific protein-tyrosine kinase) (p56-LCK)
Gene: LCK

Interactor 2: CSF3R (P40223)
Granulocyte colony-stimulating factor receptor (G-CSF receptor) (G-CSF-R) (CD antigen CD114)
Gene: CSF3R

Species: Mus musculus

Source: innatedb

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.80	0.553

Property	Details
Experiments	9790917
Identification Methods	far western blotting
Interaction Type	physical association

Property	Details
Interacting Pfam domains	PK_Tyr_Ser-Thr~fn3, SH2~fn3
Common GO terms	-
Homologous interactions	13

Homologous interactions

Color coding for hit scores

	1 509 Mm			1 837
+	Mm
		435879 HCK_MOUSE (1-509): 0: 592: 64.44		CSF3R_MOUSE (1-837): 3.29e-171: 518: 100.00
+	Hs
		442875 HCK_HUMAN (1-509): 0: 591: 65.63		CSF3R_HUMAN (1-837): 5.56e-157: 481: 60.60
+	Hs
		433961 LYN_HUMAN (1-509): 0: 566: 63.37		CSF3R_HUMAN (1-837): 5.56e-157: 481: 60.60
+	Hs
		442787 HCK_HUMAN (1-509): 0: 591: 65.63		IL6RB_HUMAN (7-814): 3.29e-104: 344: 22.59
+	Hs
		412016 FYN_HUMAN (1-507): 0: 591: 54.03		PTPRD_HUMAN (123-834): 3.65e-69: 252: 11.84
+	Hs
		411565 LCK_HUMAN (1-509): 0: 634: 96.86		PTPRF_HUMAN (26-574): 9.77e-42: 167: 12.08
+	Mm
		56907 FYN_MOUSE (1-507): 0: 590: 53.85		PTPRF_MOUSE (9-574): 1.08e-46: 183: 13.57
+	Hs
		411959 FYN_HUMAN (1-507): 0: 591: 54.03		PTPRF_HUMAN (26-574): 9.77e-42: 167: 12.08
+	Hs
		433804 LYN_HUMAN (1-509): 0: 566: 63.37		SDK2_HUMAN (22-834): 6.07e-38: 155: 9.63
+	Hs
		434019 LYN_HUMAN (1-509): 0: 566: 63.37		ROBO2_HUMAN (230-820): 1.34e-21: 103: 10.24
+	Dm
		53796 ABL_DROME (43-502): 6.85e-167: 514: 42.25		A1Z921_DROME (10-514): 5.06e-38: 155: 12.64
+	Dm
		337644 ABL_DROME (43-502): 6.85e-167: 514: 42.25		LAR_DROME (31-598): 5.6e-37: 152: 11.95
+	Hs
		560468 TEC_HUMAN (7-503): 1e-160: 471: 32.82		PRLR_HUMAN (122-342): 1.27e-51: 193: 24.44