HitPredict

Interactor 1: H1T (P06349)
Histone H1t
Gene: H1-6

Interactor 2: Q6P751 (Q6P751)
Cyclin-dependent kinase 2 (EC 2.7.11.22) (Cell division protein kinase 2)
Gene: Cdk2

Species: Rattus norvegicus

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.41	0.50	0.457

Property	Details
Experiments	15631990
Identification Methods	enzymatic study
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 208 Rn			1 298
+	Hs
		559328 H13_HUMAN (1-143): 4.83e-20: 86.2: 58.74		CDK2_HUMAN (1-298): 1.46e-166: 465: 98.99
+	Rn
		88903 H11_RAT (1-122): 1.2e-19: 84.7: 59.84		Q6P751_RAT (1-298): 3.38e-166: 464: 100.00
+	Hs
		558990 H15_HUMAN (1-117): 6.52e-18: 80.4: 61.86		CDK2_HUMAN (1-298): 1.46e-166: 465: 98.99
+	Hs
		625377 H11_HUMAN (40-150): 4.45e-14: 70: 61.26		CDK2_HUMAN (1-298): 1.46e-166: 465: 98.99
+	Mm
		794643 H11_MOUSE (1-123): 1.22e-18: 82: 60.16		CDK2_MOUSE (1-298): 1.59e-157: 444: 86.13
+	Mm
		794656 H15_MOUSE (17-145): 5.4e-18: 80.4: 61.24		CDK2_MOUSE (1-298): 1.59e-157: 444: 86.13
+	Mm
		550489 H12_MOUSE (34-117): 2.68e-14: 70.4: 76.19		CDK2_MOUSE (1-298): 1.59e-157: 444: 86.13
+	Hs
		414717 H13_HUMAN (1-143): 4.83e-20: 86.2: 58.74		CDK1_HUMAN (1-289): 2.57e-143: 406: 66.55
+	Rn
		88899 H11_RAT (1-122): 1.2e-19: 84.7: 59.84		CDK1_RAT (1-289): 2.77e-143: 406: 65.86
+	Hs
		414716 H15_HUMAN (1-117): 6.52e-18: 80.4: 61.86		CDK1_HUMAN (1-289): 2.57e-143: 406: 66.55
+	Mm
		509472 H11_MOUSE (1-123): 1.22e-18: 82: 60.16		CDK1_MOUSE (1-289): 2.76e-142: 404: 65.86
+	Hs
		414874 H11_HUMAN (40-150): 4.45e-14: 70: 61.26		CDK1_HUMAN (1-289): 2.57e-143: 406: 66.55
+	Mm
		794639 H11_MOUSE (1-123): 1.22e-18: 82: 60.16		CDK5_MOUSE (1-292): 2.01e-138: 394: 59.73
+	Mm
		509461 H12_MOUSE (34-117): 2.68e-14: 70.4: 76.19		CDK1_MOUSE (1-289): 2.76e-142: 404: 65.86
+	Hs
		559065 H15_HUMAN (1-117): 6.52e-18: 80.4: 61.86		CDK5_HUMAN (1-292): 1.73e-138: 394: 59.73
+	Hs
		559654 H12_HUMAN (31-134): 4.69e-18: 80.4: 69.23		CDK5_HUMAN (1-292): 1.73e-138: 394: 59.73
+	Hs
		489003 H14_HUMAN (18-117): 2.68e-16: 75.8: 69.00		CDK5_HUMAN (1-292): 1.73e-138: 394: 59.73
+	Hs
		559352 H13_HUMAN (1-143): 4.83e-20: 86.2: 58.74		CDK7_HUMAN (2-298): 2.14e-124: 360: 43.67
+	Hs
		559612 H12_HUMAN (31-134): 4.69e-18: 80.4: 69.23		CDK7_HUMAN (2-298): 2.14e-124: 360: 43.67
+	Hs
		488949 H14_HUMAN (18-117): 2.68e-16: 75.8: 69.00		CDK7_HUMAN (2-298): 2.14e-124: 360: 43.67