HitPredict

Interactor 1: PRGR (P06401)
Progesterone receptor (PR) (Nuclear receptor subfamily 3 group C member 3)
Gene: PGR

Interactor 2: NCOR2 (Q9Y618)
Nuclear receptor corepressor 2 (N-CoR2) (CTG repeat protein 26) (SMAP270) (Silencing mediator of retinoic acid and thyroid hormone receptor) (SMRT) (T3 receptor-associating factor) (TRAC) (Thyroid-, retinoic-acid-receptor-associated corepressor)
Gene: NCOR2

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.71	0.60	0.653

Property	Details
Experiments	10757795, 12771131, 17347654
Identification Methods	pull down, two hybrid, affinity chromatography technology
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000785 - chromatin GO:0003677 - DNA binding GO:0005654 - nucleoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 933 Hs			1 2514
+	Hs
		377839 GCR_HUMAN (256-933): 3.11e-99: 330: 33.82		NCOR2_HUMAN (1-2514): 0: 908: 100.00
+	Hs
		487879 ANDR_HUMAN (122-933): 1.17e-97: 329: 29.70		NCOR2_HUMAN (1-2514): 0: 908: 100.00
+	Hs
		261372 PRGR_HUMAN (1-933): 3.14e-133: 424: 100.00		NCOR1_HUMAN (1-2514): 9.88e-128: 453: 34.38
+	Hs
		261370 GCR_HUMAN (256-933): 3.11e-99: 330: 33.82		NCOR1_HUMAN (1-2514): 9.88e-128: 453: 34.38
+	Hs
		261380 ANDR_HUMAN (122-933): 1.17e-97: 329: 29.70		NCOR1_HUMAN (1-2514): 9.88e-128: 453: 34.38
+	Hs
		261493 NR1H3_HUMAN (473-916): 1.45e-95: 310: 20.97		NCOR1_HUMAN (1-2514): 9.88e-128: 453: 34.38
+	Hs
		377792 GCR_HUMAN (256-933): 3.11e-99: 330: 33.82		RCOR1_HUMAN (388-705): 2.51e-45: 174: 22.05
+	Hs
		487826 ANDR_HUMAN (122-933): 1.17e-97: 329: 29.70		RCOR1_HUMAN (388-705): 2.51e-45: 174: 22.05
+	Hs
		377762 GCR_HUMAN (256-933): 3.11e-99: 330: 33.82		RCOR3_HUMAN (351-810): 1.25e-41: 163: 20.65
+	Hs
		487804 ANDR_HUMAN (122-933): 1.17e-97: 329: 29.70		RCOR3_HUMAN (351-810): 1.25e-41: 163: 20.65
+	Hs
		377537 GCR_HUMAN (256-933): 3.11e-99: 330: 33.82		MUC16_HUMAN (2-2512): 2.7e-35: 151: 7.92
+	Mm
		1206787 NR1H3_MOUSE (483-916): 2.77e-96: 311: 20.32		Q8BK32_MOUSE (1-280): 1.47e-40: 155: 49.66
+	Hs
		377624 GCR_HUMAN (256-933): 3.11e-99: 330: 33.82		MINT_HUMAN (80-1321): 6.8e-20: 100: 8.11
+	Hs
		377832 GCR_HUMAN (256-933): 3.11e-99: 330: 33.82		PRC2C_HUMAN (1-1819): 3.07e-18: 94.7: 7.02
+	Hs
		377615 GCR_HUMAN (256-933): 3.11e-99: 330: 33.82		CIC_HUMAN (7-2131): 8.47e-18: 93.5: 9.33
+	Hs
		487695 ANDR_HUMAN (122-933): 1.17e-97: 329: 29.70		CIC_HUMAN (7-2131): 8.47e-18: 93.5: 9.33
+	Hs
		487596 ANDR_HUMAN (122-933): 1.17e-97: 329: 29.70		KMT2C_HUMAN (679-1264): 4.24e-16: 88: 11.93
+	Hs
		510035 ERR1_HUMAN (496-855): 3.68e-96: 311: 27.50		CIC_HUMAN (7-2131): 8.47e-18: 93.5: 9.33
+	Hs
		377539 GCR_HUMAN (256-933): 3.11e-99: 330: 33.82		TITIN_HUMAN (1125-2056): 5.55e-11: 70.9: 8.61
+	Dm
		558435 7UP1_DROME (372-913): 5.7e-96: 314: 18.86		Q86BH2_DROME (1390-2499): 5.45e-13: 77.3: 8.44