Protein: RNF38
E3 ubiquitin-protein ligase RNF38 (EC 2.3.2.27) (RING finger protein 38) (RING-type E3 ubiquitin transferase RNF38)

Gene: RNF38
Organism: Homo sapiens
Interactions: 106
UniProt ID: Q9H0F5

Gene Ontology (top 5):
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0008270 - zinc ion binding
GO:0008584 - male gonad development
GO:0016567 - protein ubiquitination

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

982319

UB2D2
Ubiquitin-conjugating enzyme E2 D2

4

20

Small-scale

0.896

High

1429964

RNF38
E3 ubiquitin-protein ligase RNF38

4

15

Small-scale

0.885

High

957840

UBE2N
Ubiquitin-conjugating enzyme E2 N

1

20

Small-scale

0.710

High

906780

UB2D1
Ubiquitin-conjugating enzyme E2 D1

1

20

High-throughput

0.698

High

957196

UB2D3
Ubiquitin-conjugating enzyme E2 D3

1

20

High-throughput

0.698

High

971059

UBE2H
Ubiquitin-conjugating enzyme E2 H

1

20

High-throughput

0.698

High

1294567

DZIP3
E3 ubiquitin-protein ligase DZIP3

1

12

High-throughput

0.698

High

1429974

UB2D4
Ubiquitin-conjugating enzyme E2 D4

1

20

High-throughput

0.698

High

508595

UBC
Polyubiquitin-C [Cleaved into: Ubiquitin]

1

17

Small-scale

0.692

High

414589

P53
Cellular tumor antigen p53

2

6

Small-scale

0.634

High

1429965

RN208
RING finger protein 208

2

4

High-throughput

0.606

High

1068303

AHNK
Neuroblast differentiation-associated protein AHNAK

2

1

Small-scale

0.584

High

1287929

LDB1
LIM domain-binding protein 1

2

4

Small-scale

0.584

High

950677

KR108
Keratin-associated protein 10-8

2

2

High-throughput

0.553

High

1133172

LASP1
LIM and SH3 domain protein 1

2

1

High-throughput

0.553

High

1186554

KR212
Keratin-associated protein 21-2

2

1

High-throughput

0.553

High

1186914

KR195
Keratin-associated protein 19-5

2

1

High-throughput

0.553

High

1213831

KPRP
Keratinocyte proline-rich protein

2

1

High-throughput

0.553

High

1351664

OXER1
Oxoeicosanoid receptor 1

2

2

High-throughput

0.553

High

943313

RBM11
Splicing regulator RBM11

1

2

High-throughput

0.541

High

1331914

DTX3
Probable E3 ubiquitin-protein ligase DTX3

1

3

High-throughput

0.541

High

1429976

RN114
E3 ubiquitin-protein ligase RNF114

1

7

High-throughput

0.541

High

843967

HD
Huntingtin

1

1

High-throughput

0.515

High

927536

ATX1
Ataxin-1

1

1

High-throughput

0.515

High

142616

IMA3
Importin subunit alpha-3

1

1

High-throughput

0.501

High

861771

NEDD4
E3 ubiquitin-protein ligase NEDD4

1

8

High-throughput

0.501

High

862440

YAP1
Transcriptional coactivator YAP1

1

9

High-throughput

0.501

High

1029937

RUNX1
Runt-related transcription factor 1

1

2

Small-scale

0.501

High

1307635

ZDH17
Palmitoyltransferase ZDHHC17

1

4

High-throughput

0.494

High

123825

MYO1C
Unconventional myosin-Ic

1

10

Small-scale

0.479

High

171325

MYPT1
Protein phosphatase 1 regulatory subunit 12A

1

3

Small-scale

0.479

High

186801

P73
Tumor protein p73

1

6

High-throughput

0.479

High

224793

ACTN4
Alpha-actinin-4

1

3

Small-scale

0.479

High

326030

UBR5
E3 ubiquitin-protein ligase UBR5

1

9

Small-scale

0.479

High

437338

K2C8
Keratin, type II cytoskeletal 8

1

4

Small-scale

0.479

High

446040

ENOA
Alpha-enolase

1

2

Small-scale

0.479

High

449787

H2B1J
Histone H2B type 1-J

1

2

Small-scale

0.479

High

475778

K2C7
Keratin, type II cytoskeletal 7

1

4

Small-scale

0.479

High

476389

K1C16
Keratin, type I cytoskeletal 16

1

9

Small-scale

0.479

High

535524

BIP
Endoplasmic reticulum chaperone BiP

1

2

Small-scale

0.479

High

612777

RL7
Large ribosomal subunit protein uL30

1

1

Small-scale

0.479

High

623532

RO52
E3 ubiquitin-protein ligase TRIM21

1

5

Small-scale

0.479

High

639406

5NTD
5'-nucleotidase

1

1

Small-scale

0.479

High

711190

PTN6
Tyrosine-protein phosphatase non-receptor type 6

1

6

Small-scale

0.479

High

773273

MYH10
Myosin-10

1

5

Small-scale

0.479

High

869976

ATPO
ATP synthase peripheral stalk subunit OSCP, mitochondrial

1

2

Small-scale

0.479

High

949206

TPIS
Triosephosphate isomerase

1

1

Small-scale

0.479

High

981691

RAN
GTP-binding nuclear protein Ran

1

15

Small-scale

0.479

High

1017197

H33
Histone H3.3

1

1

Small-scale

0.479

High

1093308

FLII
Protein flightless-1 homolog

1

2

Small-scale

0.479

High

1259638

H2AV
Histone H2A.V

1

6

Small-scale

0.479

High

1359449

LMO7
LIM domain only protein 7

1

6

Small-scale

0.479

High

1394520

PAWR
PRKC apoptosis WT1 regulator protein

1

1

Small-scale

0.479

High

1419853

UACA
Uveal autoantigen with coiled-coil domains and ankyrin repeats

1

7

Small-scale

0.479

High

1429966

P63
Tumor protein 63

1

6

High-throughput

0.479

High

1429968

RAI14
Ankycorbin

1

7

Small-scale

0.479

High

1429971

PARP4
Protein mono-ADP-ribosyltransferase PARP4

1

2

Small-scale

0.479

High

1429973

MYO6
Unconventional myosin-VI

1

8

Small-scale

0.479

High

876165

TCPE
T-complex protein 1 subunit epsilon

1

3

High-throughput

0.470

High

183365

ZN185
Zinc finger protein 185

1

0

Small-scale

0.458

High

977080

CNBP
CCHC-type zinc finger nucleic acid binding protein

1

0

Small-scale

0.458

High

984973

RL31
Large ribosomal subunit protein eL31

1

0

Small-scale

0.458

High

1010367

BASP1
Brain acid soluble protein 1

1

0

Small-scale

0.458

High

1118251

BLMH
Bleomycin hydrolase

1

0

Small-scale

0.458

High

1122220

SPIDR
DNA repair-scaffolding protein

1

0

Small-scale

0.458

High

1226804

AR6P4
ADP-ribosylation factor-like protein 6-interacting protein 4

1

0

Small-scale

0.458

High

1429967

LYAR
Cell growth-regulating nucleolar protein

1

0

Small-scale

0.458

High

227965

MYO1B
Unconventional myosin-Ib

1

11

Small-scale

0.437

High

276628

LX12B
Arachidonate 12-lipoxygenase, 12R-type

1

5

Small-scale

0.437

High

456273

CATD
Cathepsin D

1

1

Small-scale

0.437

High

569215

CD59
CD59 glycoprotein

1

1

Small-scale

0.437

High

698366

MAP4
Microtubule-associated protein 4

1

2

Small-scale

0.437

High

801516

HSPA9
Stress-70 protein, mitochondrial

1

4

Small-scale

0.437

High

866816

CAZA2
F-actin-capping protein subunit alpha-2

1

2

Small-scale

0.437

High

867408

CAPZB
F-actin-capping protein subunit beta

1

1

Small-scale

0.437

High

952643

MYL6
Myosin light polypeptide 6

1

5

Small-scale

0.437

High

1010713

DCD
Dermcidin

1

1

Small-scale

0.437

High

1047480

K1C17
Keratin, type I cytoskeletal 17

1

10

Small-scale

0.437

High

1062296

TGM3
Protein-glutamine gamma-glutamyltransferase E

1

1

Small-scale

0.437

High

1117472

SPTN1
Spectrin alpha chain, non-erythrocytic 1

1

5

Small-scale

0.437

High

1128547

DSC3
Desmocollin-3

1

5

Small-scale

0.437

High

1143258

PLEC
Plectin

1

3

Small-scale

0.437

High

1160755

DREB
Drebrin

1

1

Small-scale

0.437

High

1229865

CYTSA
Cytospin-A

1

9

Small-scale

0.437

High

1250777

MPRIP
Myosin phosphatase Rho-interacting protein

1

9

Small-scale

0.437

High

1251511

CD109
CD109 antigen

1

6

Small-scale

0.437

High

1277629

K1C27
Keratin, type I cytoskeletal 27

1

10

Small-scale

0.437

High

1289981

LUZP1
Leucine zipper protein 1

1

9

Small-scale

0.437

High

1356706

TGFA1
Transforming growth factor-beta receptor-associated protein 1

1

2

Small-scale

0.437

High

1365589

MY18A
Unconventional myosin-XVIIIa

1

7

Small-scale

0.437

High

1385425

EFHD2
EF-hand domain-containing protein D2

1

7

Small-scale

0.437

High

1399455

SPB12
Serpin B12

1

8

Small-scale

0.437

High

1429969

GBG12

1

2

Small-scale

0.437

High

1429970

LIMA1
LIM domain and actin-binding protein 1

1

5

Small-scale

0.437

High

1429972

COR1C
Coronin-1C

1

3

Small-scale

0.437

High

1429975

MYO5A
Unconventional myosin-Va

1

6

Small-scale

0.437

High

70471

CRTP1
Cysteine-rich tail protein 1

2

0

High-throughput

0.316

High

1186706

KRA62
Keratin-associated protein 6-2

2

0

High-throughput

0.316

High

1307065

KR111
Keratin-associated protein 11-1

2

0

High-throughput

0.316

High

1307095

KRA81
Keratin-associated protein 8-1

2

0

High-throughput

0.316

High

1307117

KRA71
Keratin-associated protein 7-1

2

0

High-throughput

0.316

High

301687

WFS1
Wolframin

1

0

High-throughput

0.268

Low

275196

GGCT
Gamma-glutamylcyclotransferase

1

0

Small-scale

0.249

Low

1256989

FBX50
F-box only protein 50

1

0

Small-scale

0.249

Low

1409687

ARP5L
Actin-related protein 2/3 complex subunit 5-like protein

1

0

Small-scale

0.249

Low


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Last updated: 11Aug2025