HitPredict

Interactor 1: P53 (P04637)
Cellular tumor antigen p53 (Antigen NY-CO-13) (Phosphoprotein p53) (Tumor suppressor p53)
Gene: TP53

Interactor 2: JIP3 (Q9UPT6)
C-Jun-amino-terminal kinase-interacting protein 3 (JIP-3) (JNK-interacting protein 3) (JNK MAP kinase scaffold protein 3) (Mitogen-activated protein kinase 8-interacting protein 3)
Gene: MAPK8IP3

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	31152661
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0043066 - negative regulation of apoptotic process GO:0050821 - protein stabilization
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 393 Hs			1 1336
+	Hs
		243879 P53_HUMAN (1-393): 0: 619: 100.00		JIP4_HUMAN (6-1336): 0: 609: 54.29
+	Hs
		414437 P53_HUMAN (1-393): 0: 619: 100.00		ARHGH_HUMAN (364-1331): 6.79e-152: 508: 20.26
+	Hs
		156830 P53_HUMAN (1-393): 0: 619: 100.00		CTRO_HUMAN (34-768): 1.17e-34: 147: 10.40
+	Hs
		413774 P53_HUMAN (1-393): 0: 619: 100.00		ROCK1_HUMAN (275-785): 9.68e-21: 101: 9.42
+	Hs
		413308 P53_HUMAN (1-393): 0: 619: 100.00		MYH9_HUMAN (333-903): 1.47e-18: 94.5: 8.35
+	Hs
		413132 P53_HUMAN (1-393): 0: 619: 100.00		DESP_HUMAN (41-792): 2.63e-16: 87.2: 13.03
+	Hs
		414928 P53_HUMAN (1-393): 0: 619: 100.00		MYH4_HUMAN (401-909): 7.18e-13: 76: 11.40