HitPredict

Interactor 1: TPM3 (P06753)
Tropomyosin alpha-3 chain (Gamma-tropomyosin) (Tropomyosin-3) (Tropomyosin-5) (hTM5)
Gene: TPM3

Interactor 2: IQGA1 (P46940)
Ras GTPase-activating-like protein IQGAP1 (p195)
Gene: IQGAP1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	26496610
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0005884 - actin filament GO:0051015 - actin filament binding GO:0070062 - extracellular exosome
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1 285 Hs			1 1657
+	Hs
		451214 TPM1_HUMAN (2-285): 2.54e-44: 153: 91.20		IQGA1_HUMAN (1-1657): 0: 1732: 100.00
+	Hs
		434360 TPM2_HUMAN (2-285): 1.42e-39: 141: 86.27		IQGA1_HUMAN (1-1657): 0: 1732: 100.00
+	Hs
		809261 TPM4_HUMAN (43-285): 1.76e-33: 124: 69.96		IQGA1_HUMAN (1-1657): 0: 1732: 100.00
+	Hs
		110797 H7BYY1_HUMAN (2-228): 1.39e-10: 62.2: 21.37		IQGA1_HUMAN (1-1657): 0: 1732: 100.00
+	Hs
		434423 TPM2_HUMAN (2-285): 1.42e-39: 141: 86.27		SYGP1_HUMAN (635-1477): 1.49e-108: 380: 12.26