Interactor 1: TPM3 (P06753)
Tropomyosin alpha-3 chain (Gamma-tropomyosin) (Tropomyosin-3) (Tropomyosin-5) (hTM5)
Gene: TPM3

Interactor 2: TPM4 (P67936)
Tropomyosin alpha-4 chain (TM30p1) (Tropomyosin-4)
Gene: TPM4

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.84 1.00 0.920

The method score is based on:

Property Details
Experiments 33961781, 32296183, 34349018, 35235311, unassigned1304
Identification Methods affinity chromatography technology, two hybrid, cross-linking study, validated two hybrid, two hybrid array, two hybrid prey pooling approach, anti tag coimmunoprecipitation
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains Tropomyosin~Tropomyosin
Common GO terms GO:0001725 - stress fiber
GO:0005829 - cytosol
GO:0005856 - cytoskeleton
GO:0005862 - muscle thin filament tropomyosin
GO:0005884 - actin filament
and 4 others

more...

Homologous interactions 15

Homologous interactions

Color coding for hit scores

1 285
Hs

1 248
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024