HitPredict

Interactor 1: TPM3 (P06753)
Tropomyosin alpha-3 chain (Gamma-tropomyosin) (Tropomyosin-3) (Tropomyosin-5) (hTM5)
Gene: TPM3

Interactor 2: HOOK3 (Q86VS8)
Protein Hook homolog 3 (h-hook3) (hHK3)
Gene: HOOK3

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.50	0.437

Property	Details
Experiments	28718761
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 285 Hs			1 718
+	Hs
		419021 TPM3_HUMAN (1-285): 3.63e-44: 153: 100.00		HOOK2_HUMAN (6-718): 8.03e-39: 155: 45.95
+	Dm
		419108 TPM1_DROME (2-282): 8.67e-51: 171: 45.97		MYSN_DROME (49-462): 1.6e-10: 67.1: 13.60
+	Hs
		451288 TPM1_HUMAN (2-285): 2.54e-44: 153: 91.20		DLG5_HUMAN (171-610): 2.12e-15: 82.7: 17.71
+	Hs
		419011 TPM3_HUMAN (1-285): 3.63e-44: 153: 100.00		MY18A_HUMAN (250-691): 1.59e-09: 63.8: 17.03
+	Hs
		451293 TPM1_HUMAN (2-285): 2.54e-44: 153: 91.20		MY18A_HUMAN (250-691): 1.59e-09: 63.8: 17.03
+	Hs
		418895 TPM3_HUMAN (1-285): 3.63e-44: 153: 100.00		MYH9_HUMAN (23-360): 8.18e-09: 61.5: 11.27
+	Hs
		451201 TPM1_HUMAN (2-285): 2.54e-44: 153: 91.20		MYH9_HUMAN (23-360): 8.18e-09: 61.5: 11.27
+	Dm
		828653 TPM4_DROME (58-285): 6.75e-09: 58.4: 17.54		Q8SX64_DROME (11-706): 2.96e-37: 152: 16.97
+	Hs
		434415 TPM2_HUMAN (2-285): 1.42e-39: 141: 86.27		MY18A_HUMAN (250-691): 1.59e-09: 63.8: 17.03
+	Hs
		434354 TPM2_HUMAN (2-285): 1.42e-39: 141: 86.27		MYH9_HUMAN (23-360): 8.18e-09: 61.5: 11.27
+	Hs
		932031 TPM4_HUMAN (43-285): 1.76e-33: 124: 69.96		MY18A_HUMAN (250-691): 1.59e-09: 63.8: 17.03
+	Hs
		724765 TPM4_HUMAN (43-285): 1.76e-33: 124: 69.96		MYH9_HUMAN (23-360): 8.18e-09: 61.5: 11.27
+	Rn
		222476 MRCKB_RAT (3-285): 1.56e-12: 69.5: 14.09		MRCKA_RAT (328-718): 3.5e-21: 101: 14.08
+	Hs
		1231043 MRCKB_HUMAN (12-285): 1.02e-11: 67.2: 14.92		K2C78_HUMAN (276-606): 5.85e-21: 99.3: 19.53
+	Mm
		358682 LAMB1_MOUSE (3-211): 2.99e-16: 80.8: 19.05		LAMA1_MOUSE (80-616): 4.77e-15: 81.9: 15.40
+	Rn
		1186812 MRCKB_RAT (3-285): 1.56e-12: 69.5: 14.09		MRCKB_RAT (70-519): 1.55e-13: 76.5: 13.03
+	Hs
		1268126 MRCKB_HUMAN (12-285): 1.02e-11: 67.2: 14.92		MY18A_HUMAN (250-691): 1.59e-09: 63.8: 17.03
+	Hs
		110802 H7BYY1_HUMAN (2-228): 1.39e-10: 62.2: 21.37		MY18A_HUMAN (250-691): 1.59e-09: 63.8: 17.03
+	Hs
		110796 H7BYY1_HUMAN (2-228): 1.39e-10: 62.2: 21.37		MYH9_HUMAN (23-360): 8.18e-09: 61.5: 11.27