HitPredict

Interactor 1: TPM3 (P06753)
Tropomyosin alpha-3 chain (Gamma-tropomyosin) (Tropomyosin-3) (Tropomyosin-5) (hTM5)
Gene: TPM3

Interactor 2: SYCE1 (Q8N0S2)
Synaptonemal complex central element protein 1 (Cancer/testis antigen 76) (CT76)
Gene: SYCE1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.71	0.50	0.600

Property	Details
Experiments	25416956, 25910212
Identification Methods	two hybrid, two hybrid prey pooling approach, two hybrid array, validated two hybrid, split luciferase complementation, two hybrid bait and prey pooling approach
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	3

Homologous interactions

Color coding for hit scores

	1 285 Hs			1 351
+	Hs
		451280 TPM1_HUMAN (2-285): 2.54e-44: 153: 91.20		SYCE1_HUMAN (1-351): 4.16e-148: 423: 100.00
+	Hs
		434406 TPM2_HUMAN (2-285): 1.42e-39: 141: 86.27		SYCE1_HUMAN (1-351): 4.16e-148: 423: 100.00
+	Hs
		1138393 Q5VU62_HUMAN (128-285): 1.66e-39: 137: 100.00		SYCE1_HUMAN (1-351): 4.16e-148: 423: 100.00