Interactor 1: IGF1 (P05019)
Insulin-like growth factor 1 (Insulin-like growth factor I) (IGF-I) (Mechano growth factor) (MGF) (Somatomedin-C)
Gene: IGF1
Interactor 2: IDE (P14735)
Insulin-degrading enzyme (EC 3.4.24.56) (Abeta-degrading protease) (Insulin protease) (Insulinase) (Insulysin)
Gene: IDE
Species: Homo sapiens
Source: biogrid
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.41 | 1.00 | 0.647 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 1733942 |
| Identification Methods | pull down |
| Interaction Type | direct interaction |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | Insulin~Peptidase_M16, Insulin~Peptidase_M16_C, Insulin~Peptidase_M16_M, Insulin~PqqF-like_C_4 |
| Common GO terms | GO:0005615 - extracellular space GO:0008286 - insulin receptor signaling pathway |
| Homologous interactions | 2 |
Homologous interactions
Color coding for hit scores 
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Service provided by Combinatics, Japan
Last updated: 11Aug2025
