HitPredict

Interactor 1: ERG12 (P07277)
Mevalonate kinase (MK) (MvK) (EC 2.7.1.36) (Ergosterol biosynthesis protein 12) (Regulation of autonomous replication protein 1)
Gene: ERG12

Interactor 2: SSB1 (P11484)
Ribosome-associated molecular chaperone SSB1 (EC 3.6.4.10) (Cold-inducible protein YG101) (Heat shock protein SSB1) (Hsp70 chaperone Ssb)
Gene: SSB1

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.54	0.60	0.571

Property	Details
Experiments	22940862, 19536198
Identification Methods	affinity chromatography technology, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005524 - ATP binding GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0005829 - cytosol
Homologous interactions	4

Homologous interactions

Color coding for hit scores

	1 443 Sc			1 613
+	Sc
		425560 ERG12_YEAST (1-443): 6.4e-179: 509: 100.00		SSB2_YEAST (1-613): 0: 1118: 99.35
+	Sc
		381410 GAL1_YEAST (3-382): 1.32e-85: 273: 14.10		SSB1_YEAST (1-613): 0: 1128: 100.00
+	Hs
		503935 KIME_HUMAN (1-409): 7.9e-138: 402: 31.16		HSP7C_HUMAN (5-612): 0: 900: 59.84
+	Sc
		510081 GAL3_YEAST (1-259): 4.24e-46: 168: 15.87		SSB1_YEAST (1-613): 0: 1128: 100.00