HitPredict

Interactor 1: FGF1 (P05230)
Fibroblast growth factor 1 (FGF-1) (Acidic fibroblast growth factor) (aFGF) (Endothelial cell growth factor) (ECGF) (Heparin-binding growth factor 1) (HBGF-1)
Gene: FGF1

Interactor 2: Q8NI16 (Q8NI16)
Fibroblast growth factor receptor 3 (EC 2.7.10.1)
Gene: FGFR3

Species: Homo sapiens

Source: dip

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	9045692
Identification Methods	coimmunoprecipitation
Interaction Type	physical association

Property	Details
Interacting Pfam domains	FGF~I-set
Common GO terms	GO:0008284 - positive regulation of cell population proliferation
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 155 Hs			1 771
+	Hs
		426939 FGF1_HUMAN (1-155): 2.96e-74: 220: 100.00		FGFR3_HUMAN (1-771): 0: 775: 95.47
+	Hs
		650061 FGF9_HUMAN (11-155): 6.47e-67: 203: 35.85		FGFR3_HUMAN (1-771): 0: 775: 95.47
+	Hs
		640746 FGF7_HUMAN (13-153): 1.88e-65: 199: 35.66		FGFR3_HUMAN (1-771): 0: 775: 95.47
+	Hs
		478448 FGF2_HUMAN (1-154): 7.44e-63: 196: 54.14		FGFR3_HUMAN (1-771): 0: 775: 95.47
+	Mm
		926309 FGF9_MOUSE (11-155): 7.37e-67: 203: 35.85		FGFR3_MOUSE (1-771): 0: 754: 89.00
+	Hs
		426937 FGF1_HUMAN (1-155): 2.96e-74: 220: 100.00		FGFR2_HUMAN (2-763): 0: 724: 64.22
+	Hs
		641127 FGF9_HUMAN (11-155): 6.47e-67: 203: 35.85		FGFR2_HUMAN (2-763): 0: 724: 64.22
+	Hs
		193063 FGF10_HUMAN (14-154): 5.1e-66: 201: 32.87		FGFR2_HUMAN (2-763): 0: 724: 64.22
+	Hs
		640745 FGF7_HUMAN (13-153): 1.88e-65: 199: 35.66		FGFR2_HUMAN (2-763): 0: 724: 64.22
+	Hs
		478445 FGF2_HUMAN (1-154): 7.44e-63: 196: 54.14		FGFR2_HUMAN (2-763): 0: 724: 64.22
+	Hs
		426932 FGF1_HUMAN (1-155): 2.96e-74: 220: 100.00		FGFR1_HUMAN (2-763): 0: 692: 60.46
+	Mm
		591447 FGF9_MOUSE (11-155): 7.37e-67: 203: 35.85		FGFR1_MOUSE (2-763): 0: 694: 60.59
+	Hs
		541358 FGF9_HUMAN (11-155): 6.47e-67: 203: 35.85		FGFR1_HUMAN (2-763): 0: 692: 60.46
+	Hs
		193061 FGF10_HUMAN (14-154): 5.1e-66: 201: 32.87		FGFR1_HUMAN (2-763): 0: 692: 60.46
+	Mm
		585426 FGF2_MOUSE (1-154): 8.75e-64: 194: 53.21		FGFR2_MOUSE (2-763): 0: 699: 62.81
+	Hs
		478439 FGF2_HUMAN (1-154): 7.44e-63: 196: 54.14		FGFR1_HUMAN (2-763): 0: 692: 60.46
+	Mm
		585425 FGF2_MOUSE (1-154): 8.75e-64: 194: 53.21		FGFR1_MOUSE (2-763): 0: 694: 60.59
+	Hs
		426938 FGF1_HUMAN (1-155): 2.96e-74: 220: 100.00		FGFR4_HUMAN (1-767): 0: 657: 60.62
+	Hs
		478447 FGF2_HUMAN (1-154): 7.44e-63: 196: 54.14		FGFR4_HUMAN (1-767): 0: 657: 60.62
+	Rn
		958070 FGF1_RAT (1-155): 1.37e-73: 218: 95.48		Q63237_RAT (7-378): 1.46e-141: 425: 50.79