HitPredict

Interactor 1: ADRB2 (P07550)
Beta-2 adrenergic receptor (Beta-2 adrenoreceptor) (Beta-2 adrenoceptor)
Gene: ADRB2

Interactor 2: CAV3 (P56539)
Caveolin-3 (M-caveolin)
Gene: CAV3

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.60	0.614

Property	Details
Experiments	28298427, 21362625
Identification Methods	two hybrid, affinity chromatography technology, ubiquitin reconstruction
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane GO:0044877 - protein-containing complex binding
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1 413 Hs			1 151
+	Mm
		578599 ADRB2_MOUSE (1-413): 2.74e-118: 352: 87.08		CAV3_MOUSE (1-150): 1.75e-77: 228: 95.33
+	Hs
		626736 NK1R_HUMAN (9-412): 1.37e-69: 227: 21.12		CAV1_HUMAN (2-151): 3.66e-78: 231: 63.33
+	Hs
		626734 NK1R_HUMAN (9-412): 1.37e-69: 227: 21.12		CAV2_HUMAN (26-150): 2.87e-56: 175: 39.20
+	Rn
		540671 5HT2A_RAT (37-340): 1.22e-39: 149: 30.06		Q3MHT6_RAT (2-151): 6.28e-76: 225: 64.00
+	Hs
		658224 5HT2C_HUMAN (53-340): 2.84e-36: 139: 32.81		CAV1_HUMAN (2-151): 3.66e-78: 231: 63.33