HitPredict

Interactor 1: CTTB2 (Q8WZ74)
Cortactin-binding protein 2 (CortBP2)
Gene: CTTNBP2

Interactor 2: TNIK (Q9UKE5)
TRAF2 and NCK-interacting protein kinase (EC 2.7.11.1)
Gene: TNIK

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	1.00	0.691

Property	Details
Experiments	32707033
Identification Methods	affinity chromatography technology, pull down
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	Ank~Pkinase, Ank_2~Pkinase, Ank_4~Pkinase
Common GO terms	GO:0098978 - glutamatergic synapse
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1663 Hs			1 1360
+	Mm
		82720 CTTB2_MOUSE (1-1663): 0: 1182: 83.89		TNIK_MOUSE (1-1360): 0: 1208: 96.10
+	Hs
		324853 CTTB2_HUMAN (1-1663): 0: 1226: 100.00		M4K4_HUMAN (1-1360): 0: 970: 59.11
+	Hs
		310105 TNKS1_HUMAN (714-1334): 1.19e-105: 371: 12.35		TNIK_HUMAN (1-1360): 0: 1235: 100.00
+	Hs
		1264911 CTTB2_HUMAN (1-1663): 0: 1226: 100.00		STK26_HUMAN (16-400): 7.78e-113: 362: 38.27
+	Hs
		131594 CTTB2_HUMAN (1-1663): 0: 1226: 100.00		STK25_HUMAN (20-410): 8.77e-113: 362: 37.91
+	Hs
		1264921 CTTB2_HUMAN (1-1663): 0: 1226: 100.00		STK24_HUMAN (20-340): 2.15e-111: 359: 43.03
+	Hs
		1350214 CT2NL_HUMAN (32-597): 1.61e-94: 322: 39.00		TNIK_HUMAN (1-1360): 0: 1235: 100.00
+	Hs
		965172 ANK2_HUMAN (553-1160): 5.69e-71: 267: 14.99		TNIK_HUMAN (1-1360): 0: 1235: 100.00
+	Mm
		949370 ANK2_MOUSE (553-1160): 6.05e-71: 267: 14.99		TNIK_MOUSE (1-1360): 0: 1208: 96.10
+	Hs
		1356406 ANR50_HUMAN (824-1284): 1.25e-56: 219: 9.85		TNIK_HUMAN (1-1360): 0: 1235: 100.00
+	Hs
		1233557 CT2NL_HUMAN (32-597): 1.61e-94: 322: 39.00		MINK1_HUMAN (1-1360): 0: 1051: 60.43
+	Hs
		324896 CT2NL_HUMAN (32-597): 1.61e-94: 322: 39.00		M4K4_HUMAN (1-1360): 0: 970: 59.11
+	Mm
		1169656 NAV1_MOUSE (981-1393): 7.56e-90: 326: 23.37		TAOK2_MOUSE (1-858): 2.53e-132: 440: 22.14
+	Hs
		1329540 TNKS2_HUMAN (573-985): 1.6e-76: 280: 18.89		TAOK2_HUMAN (1-861): 1.36e-131: 438: 22.29
+	Hs
		1023131 CT2NL_HUMAN (32-597): 1.61e-94: 322: 39.00		STK4_HUMAN (5-482): 7.72e-121: 387: 33.06
+	Hs
		1027448 CT2NL_HUMAN (32-597): 1.61e-94: 322: 39.00		STK3_HUMAN (4-485): 1.79e-115: 372: 29.28
+	Hs
		131617 CT2NL_HUMAN (32-597): 1.61e-94: 322: 39.00		STK25_HUMAN (20-410): 8.77e-113: 362: 37.91
+	Hs
		1350176 CT2NL_HUMAN (32-597): 1.61e-94: 322: 39.00		STK26_HUMAN (16-400): 7.78e-113: 362: 38.27
+	Hs
		1350219 CT2NL_HUMAN (32-597): 1.61e-94: 322: 39.00		STK24_HUMAN (20-340): 2.15e-111: 359: 43.03
+	Hs
		883501 RIPK4_HUMAN (627-829): 4.95e-29: 128: 24.53		STK3_HUMAN (4-485): 1.79e-115: 372: 29.28