HitPredict

Interactor 1: PROF1 (P07737)
Profilin-1 (Epididymis tissue protein Li 184a) (Profilin I)
Gene: PFN1

Interactor 2: ITSN1 (Q15811)
Intersectin-1 (SH3 domain-containing protein 1A) (SH3P17)
Gene: ITSN1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	34079125
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0070064 - proline-rich region binding
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 140 Hs			1 1721
+	Hs
		279831 PROF1_HUMAN (1-140): 1.1e-77: 227: 100.00		TRIO_HUMAN (154-1590): 1.54e-71: 269: 10.81
+	Hs
		430021 PROF1_HUMAN (1-140): 1.1e-77: 227: 100.00		BCR_HUMAN (732-1682): 1.5e-71: 266: 12.45
+	Hs
		430357 PROF1_HUMAN (1-140): 1.1e-77: 227: 100.00		ARHGC_HUMAN (648-1635): 3.19e-67: 253: 15.32
+	Hs
		167062 PROF1_HUMAN (1-140): 1.1e-77: 227: 100.00		ARHGB_HUMAN (1231-1469): 2.58e-20: 100: 30.65
+	Hs
		430085 PROF1_HUMAN (1-140): 1.1e-77: 227: 100.00		EPS15_HUMAN (529-913): 1.04e-10: 68.9: 12.69
+	Hs
		430206 PROF1_HUMAN (1-140): 1.1e-77: 227: 100.00		SH319_HUMAN (1079-1218): 3.12e-09: 63.9: 28.57
+	Hs
		430038 PROF1_HUMAN (1-140): 1.1e-77: 227: 100.00		NCK1_HUMAN (895-1055): 6.44e-09: 62: 27.75