HitPredict

Interactor 1: HS90A (P07900)
Heat shock protein HSP 90-alpha (EC 3.6.4.10) (Heat shock 86 kDa) (HSP 86) (HSP86) (Heat shock protein family C member 1) (Lipopolysaccharide-associated protein 2) (LAP-2) (LPS-associated protein 2) (Renal carcinoma antigen NY-REN-38)
Gene: HSP90AA1

Interactor 2: F10A1 (P50502)
Hsc70-interacting protein (Hip) (Aging-associated protein 2) (Progesterone receptor-associated p48 protein) (Protein FAM10A1) (Putative tumor suppressor ST13) (Renal carcinoma antigen NY-REN-33) (Suppression of tumorigenicity 13 protein)
Gene: ST13

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.73	1.00	0.857

Property	Details
Experiments	10642522, 22504172, 19875381
Identification Methods	pull down, affinity chromatography technology, tandem affinity purification
Interaction Type	direct interaction, physical association, association

Property	Details
Interacting Pfam domains	HSP90~TPR_8
Common GO terms	GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0006457 - protein folding GO:0070062 - extracellular exosome
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 732 Hs			1 369
+	Mm
		432427 HS90A_MOUSE (1-732): 0: 1083: 97.82		PPP5_MOUSE (91-271): 1.13e-45: 165: 21.43
+	Hs
		432363 HS90A_HUMAN (1-732): 0: 1087: 100.00		CHIP_HUMAN (89-326): 1.18e-41: 149: 15.26
+	Hs
		111936 K9JA46_HUMAN (1-732): 0: 1087: 100.00		FKBP4_HUMAN (18-277): 2e-39: 147: 16.61
+	Hs
		111937 K9JA46_HUMAN (1-732): 0: 1087: 100.00		FKBP5_HUMAN (17-284): 2.61e-39: 147: 16.14
+	Hs
		431755 HS90A_HUMAN (1-732): 0: 1087: 100.00		FKBP4_HUMAN (18-277): 2e-39: 147: 16.61
+	Hs
		431818 HS90A_HUMAN (1-732): 0: 1087: 100.00		FKBP5_HUMAN (17-284): 2.61e-39: 147: 16.14
+	Hs
		111935 K9JA46_HUMAN (1-732): 0: 1087: 100.00		PPP5_HUMAN (91-271): 3.15e-38: 144: 21.43
+	Hs
		431681 HS90A_HUMAN (1-732): 0: 1087: 100.00		PPP5_HUMAN (91-271): 3.15e-38: 144: 21.43
+	Hs
		213451 HS90A_HUMAN (1-732): 0: 1087: 100.00		SGTA_HUMAN (47-337): 7.82e-39: 142: 16.78
+	Mm
		513680 HS90B_MOUSE (19-732): 0: 1063: 86.98		PPP5_MOUSE (91-271): 1.13e-45: 165: 21.43
+	Mm
		432409 HS90A_MOUSE (1-732): 0: 1083: 97.82		FKBP4_MOUSE (18-282): 2.51e-38: 144: 15.96
+	Mm
		513709 HS90B_MOUSE (19-732): 0: 1063: 86.98		CHIP_MOUSE (91-326): 2.9e-41: 148: 16.60
+	Hs
		432268 HS90A_HUMAN (1-732): 0: 1087: 100.00		RPAP3_HUMAN (41-234): 1.35e-29: 121: 21.13
+	Hs
		213454 HS90B_HUMAN (19-732): 0: 1059: 86.13		SGTA_HUMAN (47-337): 7.82e-39: 142: 16.78
+	Hs
		297024 HS90A_HUMAN (1-732): 0: 1087: 100.00		TOM70_HUMAN (86-244): 3.55e-23: 103: 26.83
+	Hs
		111934 K9JA46_HUMAN (1-732): 0: 1087: 100.00		STIP1_HUMAN (111-220): 4.18e-20: 93.5: 25.46
+	Hs
		431574 HS90A_HUMAN (1-732): 0: 1087: 100.00		STIP1_HUMAN (111-220): 4.18e-20: 93.5: 25.46
+	Hs
		174556 HS90A_HUMAN (1-732): 0: 1087: 100.00		OGT1_HUMAN (103-355): 3.07e-19: 91.6: 12.83
+	Hs
		297025 HS90B_HUMAN (19-732): 0: 1059: 86.13		TOM70_HUMAN (86-244): 3.55e-23: 103: 26.83
+	Hs
		174561 HS90B_HUMAN (19-732): 0: 1059: 86.13		OGT1_HUMAN (103-355): 3.07e-19: 91.6: 12.83