Interactor 1: ITB1 (P05556)
Integrin beta-1 (Fibronectin receptor subunit beta) (Glycoprotein IIa) (GPIIA) (VLA-4 subunit beta) (CD antigen CD29)
Gene: ITGB1
Interactor 2: INSR (P06213)
Insulin receptor (IR) (EC 2.7.10.1) (CD antigen CD220) [Cleaved into: Insulin receptor subunit alpha; Insulin receptor subunit beta]
Gene: INSR
Species: Homo sapiens
Source: intact
Category: High-throughput
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.41 | 1.00 | 0.646 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 35384245 |
| Identification Methods | affinity chromatography technology |
| Interaction Type | physical association, association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | Integrin_beta~fn3 |
| Common GO terms | GO:0005886 - plasma membrane GO:0009897 - external side of plasma membrane GO:0010008 - endosome membrane GO:0016020 - membrane GO:0030335 - positive regulation of cell migration and 5 others more... |
| Homologous interactions | 15 |
Homologous interactions
Color coding for hit scores 
Service provided by Combinatics, Japan
Last updated: 11Aug2025