HitPredict

Interactor 1: HS90A (P07900)
Heat shock protein HSP 90-alpha (EC 3.6.4.10) (Heat shock 86 kDa) (HSP 86) (HSP86) (Heat shock protein family C member 1) (Lipopolysaccharide-associated protein 2) (LAP-2) (LPS-associated protein 2) (Renal carcinoma antigen NY-REN-38)
Gene: HSP90AA1

Interactor 2: TTC9C (Q8N5M4)
Tetratricopeptide repeat protein 9C (TPR repeat protein 9C)
Gene: TTC9C

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.65	0.50	0.574

Property	Details
Experiments	33961781, 19875381
Identification Methods	affinity chromatography technology, tandem affinity purification, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 732 Hs			1 171
+	Hs
		431781 HS90A_HUMAN (1-732): 0: 1087: 100.00		PPID_HUMAN (1-171): 4.14e-38: 135: 23.98
+	Hs
		111936 K9JA46_HUMAN (1-732): 0: 1087: 100.00		FKBP4_HUMAN (2-170): 1.94e-35: 130: 23.67
+	Hs
		431755 HS90A_HUMAN (1-732): 0: 1087: 100.00		FKBP4_HUMAN (2-170): 1.94e-35: 130: 23.67
+	Hs
		111929 K9JA46_HUMAN (1-732): 0: 1087: 100.00		AIP_HUMAN (2-171): 2.95e-35: 127: 21.05
+	Hs
		118674 HS90A_HUMAN (1-732): 0: 1087: 100.00		AIP_HUMAN (2-171): 2.95e-35: 127: 21.05
+	Mm
		432409 HS90A_MOUSE (1-732): 0: 1083: 97.82		FKBP4_MOUSE (3-170): 1.89e-35: 130: 24.41
+	Hs
		111937 K9JA46_HUMAN (1-732): 0: 1087: 100.00		FKBP5_HUMAN (2-170): 3.75e-33: 123: 21.30
+	Hs
		431818 HS90A_HUMAN (1-732): 0: 1087: 100.00		FKBP5_HUMAN (2-170): 3.75e-33: 123: 21.30
+	Hs
		111930 K9JA46_HUMAN (1-732): 0: 1087: 100.00		FKBP6_HUMAN (1-171): 1.74e-33: 122: 25.15
+	Hs
		259914 HS90A_HUMAN (1-732): 0: 1087: 100.00		FKBP6_HUMAN (1-171): 1.74e-33: 122: 25.15
+	Hs
		432312 HS90A_HUMAN (1-732): 0: 1087: 100.00		AIPL1_HUMAN (2-171): 1.64e-32: 120: 21.64
+	Hs
		111943 K9JA46_HUMAN (1-732): 0: 1087: 100.00		FKBPL_HUMAN (3-171): 1.03e-31: 118: 23.08
+	Hs
		432338 HS90A_HUMAN (1-732): 0: 1087: 100.00		FKBPL_HUMAN (3-171): 1.03e-31: 118: 23.08
+	Hs
		431850 HS90A_HUMAN (1-732): 0: 1087: 100.00		FKBP8_HUMAN (2-171): 1.63e-30: 115: 26.47
+	Mm
		432427 HS90A_MOUSE (1-732): 0: 1083: 97.82		PPP5_MOUSE (2-163): 1.11e-30: 117: 14.82
+	Hs
		118678 HS90B_HUMAN (19-732): 0: 1059: 86.13		AIP_HUMAN (2-171): 2.95e-35: 127: 21.05
+	Hs
		259915 HS90B_HUMAN (19-732): 0: 1059: 86.13		FKBP6_HUMAN (1-171): 1.74e-33: 122: 25.15
+	Mm
		513680 HS90B_MOUSE (19-732): 0: 1063: 86.98		PPP5_MOUSE (2-163): 1.11e-30: 117: 14.82
+	Hs
		213451 HS90A_HUMAN (1-732): 0: 1087: 100.00		SGTA_HUMAN (84-170): 1.1e-09: 57.7: 21.84
+	Hs
		213454 HS90B_HUMAN (19-732): 0: 1059: 86.13		SGTA_HUMAN (84-170): 1.1e-09: 57.7: 21.84