HitPredict

Interactor 1: LYN (P07948)
Tyrosine-protein kinase Lyn (EC 2.7.10.2) (Lck/Yes-related novel protein tyrosine kinase) (V-yes-1 Yamaguchi sarcoma viral related oncogene homolog) (p53Lyn) (p56Lyn)
Gene: LYN

Interactor 2: PHAG1 (Q9NWQ8)
Phosphoprotein associated with glycosphingolipid-enriched microdomains 1 (Csk-binding protein) (Transmembrane adapter protein PAG) (Transmembrane phosphoprotein Cbp)
Gene: PAG1

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.77 1.00 0.882

The method score is based on:

Property Details
Experiments 10790433, 34079125, 18070987, 23866081
Identification Methods pull down, proximity labelling technology, anti bait coimmunoprecipitation
Interaction Type direct interaction, physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains PAG~SH2
Common GO terms GO:0002250 - adaptive immune response
GO:0005886 - plasma membrane
GO:0007165 - signal transduction
GO:0045121 - membrane raft
Homologous interactions 12

Homologous interactions

Color coding for hit scores

1 512
Hs

1 432
+ Mm
+ Mm
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+ Hs
+ Mm
+ Hs
+ Hs
+ Hs
+ Mm
+ Hs
+ Rn
+ Mm

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024