HitPredict

Interactor 1: F261 (P07953)
6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 1 (6PF-2-K/Fru-2,6-P2ase 1) (PFK/FBPase 1) (6PF-2-K/Fru-2,6-P2ase liver isozyme) [Includes: 6-phosphofructo-2-kinase (EC 2.7.1.105); Fructose-2,6-bisphosphatase (EC 3.1.3.46)]
Gene: Pfkfb1

Interactor 2: F261 (P07953)
6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 1 (6PF-2-K/Fru-2,6-P2ase 1) (PFK/FBPase 1) (6PF-2-K/Fru-2,6-P2ase liver isozyme) [Includes: 6-phosphofructo-2-kinase (EC 2.7.1.105); Fructose-2,6-bisphosphatase (EC 3.1.3.46)]
Gene: Pfkfb1

Species: Rattus norvegicus

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.70 1.00 0.839

The method score is based on:

Property Details
Experiments 8634242, 11522786, 22668829
Identification Methods x-ray crystallography, two hybrid, fluorescent resonance energy transfer
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains 6PF2K~6PF2K, 6PF2K~His_Phos_1, His_Phos_1~His_Phos_1
Common GO terms GO:0003873 - 6-phosphofructo-2-kinase activity
GO:0004331 - fructose-2,6-bisphosphate 2-phosphatase activity
GO:0005524 - ATP binding
GO:0005829 - cytosol
GO:0006000 - fructose metabolic process
and 12 others

more...
Homologous interactions 14

Homologous interactions

Color coding for hit scores

1 471
Rn

1 471
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Last updated: 15 Jul 2024