HitPredict

Interactor 1: TSP1 (P07996)
Thrombospondin-1 (Glycoprotein G)
Gene: THBS1

Interactor 2: CO7A1 (Q02388)
Collagen alpha-1(VII) chain (Long-chain collagen) (LC collagen)
Gene: COL7A1

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.61	1.00	0.786

Property	Details
Experiments	18254948, 9840442
Identification Methods	two hybrid, pull down
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	EGF_3~fn3, TSP_1~VWA
Common GO terms	GO:0005576 - extracellular region GO:0005615 - extracellular space GO:0005788 - endoplasmic reticulum lumen GO:0007155 - cell adhesion GO:0062023 - collagen-containing extracellular matrix
Homologous interactions	12

Homologous interactions

Color coding for hit scores

	1 1170 Hs			1 2944
+	Hs
		172657 LAMA5_HUMAN (496-717): 7.46e-09: 62.6: 14.22		CO7A1_HUMAN (1-2944): 0: 1174: 100.00
+	Hs
		358646 TSP1_HUMAN (1-1170): 0: 804: 100.00		CO4A1_HUMAN (1118-1690): 1.47e-42: 174: 31.72
+	Hs
		358586 TSP1_HUMAN (1-1170): 0: 804: 100.00		CO2A1_HUMAN (2183-2782): 3.55e-28: 127: 42.22
+	Hs
		434609 TSP1_HUMAN (1-1170): 0: 804: 100.00		COBA1_HUMAN (1253-1713): 2.34e-20: 102: 38.61
+	Hs
		358627 TSP1_HUMAN (1-1170): 0: 804: 100.00		CO3A1_HUMAN (1258-1756): 3.21e-15: 84.7: 43.39
+	Hs
		362706 TSP1_HUMAN (1-1170): 0: 804: 100.00		FINC_HUMAN (117-501): 9.17e-14: 80.5: 16.95
+	Hs
		358450 TSP1_HUMAN (1-1170): 0: 804: 100.00		CO1A1_HUMAN (2584-2784): 3.54e-09: 65.1: 39.22
+	Hs
		1224465 UNC5B_HUMAN (491-599): 1.08e-23: 110: 34.82		NEO1_HUMAN (60-970): 8.91e-131: 453: 14.24
+	Hs
		980365 NOTC2_HUMAN (219-992): 8.55e-34: 144: 11.26		CNTN1_HUMAN (385-1176): 2.8e-48: 191: 11.19
+	Hs
		804225 NOTC1_HUMAN (582-982): 2.84e-21: 103: 12.80		CNTN1_HUMAN (385-1176): 2.8e-48: 191: 11.19
+	Hs
		362826 TENA_HUMAN (184-652): 9.86e-47: 186: 11.80		FINC_HUMAN (117-501): 9.17e-14: 80.5: 16.95
+	Hs
		804242 NOTC1_HUMAN (582-982): 2.84e-21: 103: 12.80		CO4A6_HUMAN (2534-2892): 2.3e-18: 95.2: 29.12