Interactor 1: GLI1 (P08151)
Zinc finger protein GLI1 (Glioma-associated oncogene) (Oncogene GLI)
Gene: GLI1

Interactor 2: KS6B1 (P23443)
Ribosomal protein S6 kinase beta-1 (S6K-beta-1) (S6K1) (EC 2.7.11.1) (70 kDa ribosomal protein S6 kinase 1) (P70S6K1) (p70-S6K 1) (Ribosomal protein S6 kinase I) (Serine/threonine-protein kinase 14A) (p70 ribosomal S6 kinase alpha) (p70 S6 kinase alpha) (p70 S6K-alpha) (p70 S6KA)
Gene: RPS6KB1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.55 1.00 0.747

The method score is based on:

Property Details
Experiments 22439934
Identification Methods anti bait coimmunoprecipitation, anti tag coimmunoprecipitation, protein kinase assay
Interaction Type physical association, phosphorylation reaction

The annotation score is based on:

Property Details
Interacting Pfam domains Pkinase~zf-C2H2
Common GO terms GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0005737 - cytoplasm
GO:0005829 - cytosol
Homologous interactions 5

Homologous interactions

Color coding for hit scores

1 1106
Hs

1 525
+ Hs
+ Hs
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024