Protein: PPHLN
Periphilin-1 (CDC7 expression repressor) (CR) (Gastric cancer antigen Ga50)

Gene: PPHLN, PPHLN1
Organism: Homo sapiens
Interactions: 139
UniProt ID: Q8NEY8

Gene Ontology (top 5):
GO:0003723 - RNA binding
GO:0005654 - nucleoplasm
GO:0005694 - chromosome
GO:0005794 - Golgi apparatus
GO:0005829 - cytosol

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

833928

CLK2
Dual specificity protein kinase CLK2

3

2

High-throughput

0.675

High

1203493

SKAP1
Src kinase-associated phosphoprotein 1

3

1

High-throughput

0.667

High

1201548

ZCH18
Zinc finger CCCH domain-containing protein 18

3

0

High-throughput

0.638

High

1243734

AP2M1
AP-2 complex subunit mu

3

0

High-throughput

0.638

High

834083

CLK3
Dual specificity protein kinase CLK3

2

2

High-throughput

0.628

High

1243725

HNRLL
Heterogeneous nuclear ribonucleoprotein L-like

2

1

High-throughput

0.628

High

1243745

NXF2
Nuclear RNA export factor 2

2

1

High-throughput

0.628

High

749691

BRCA1
Breast cancer type 1 susceptibility protein

2

1

High-throughput

0.614

High

1243763

LMBL1
Lethal(3)malignant brain tumor-like protein 1

2

0

High-throughput

0.602

High

843803

FXR1
RNA-binding protein FXR1

2

0

High-throughput

0.601

High

982296

1433F
14-3-3 protein eta

2

1

High-throughput

0.601

High

1243739

MPP8
M-phase phosphoprotein 8

2

1

Small-scale

0.594

High

737931

PP1G
Serine/threonine-protein phosphatase PP1-gamma catalytic subunit

2

0

High-throughput

0.585

High

1152505

Q6ICH2
Apolipoprotein B mRNA editing enzyme catalytic subunit 3D

2

2

High-throughput

0.584

High

370039

ESR1
Estrogen receptor

2

1

High-throughput

0.571

High

244677

BRD4
Bromodomain-containing protein 4

2

0

High-throughput

0.559

High

1243750

ANLN
Anillin

2

0

High-throughput

0.559

High

1243764

SNCAP
Synphilin-1

1

1

Small-scale

0.552

High

960217

CDK6
Cyclin-dependent kinase 6

1

0

Small-scale

0.545

High

1243743

SHAN3
SH3 and multiple ankyrin repeat domains protein 3

1

1

High-throughput

0.541

High

71186

HNRC2
Heterogeneous nuclear ribonucleoprotein C-like 2

1

2

High-throughput

0.536

High

157223

BACH1
Transcription regulator protein BACH1

1

1

High-throughput

0.536

High

241331

HNRC1
Heterogeneous nuclear ribonucleoprotein C-like 1

1

2

High-throughput

0.536

High

321135

PTBP3
Polypyrimidine tract-binding protein 3

1

1

High-throughput

0.536

High

432815

HNRPC
Heterogeneous nuclear ribonucleoproteins C1/C2

1

4

High-throughput

0.536

High

446708

SNRPA
U1 small nuclear ribonucleoprotein A

1

2

High-throughput

0.536

High

952042

SRSF3
Serine/arginine-rich splicing factor 3

1

1

High-throughput

0.536

High

1029005

SRSF6
Serine/arginine-rich splicing factor 6

1

1

High-throughput

0.536

High

1073804

RBMS2
RNA-binding motif, single-stranded-interacting protein 2

1

2

High-throughput

0.536

High

1092861

HNRL2
Heterogeneous nuclear ribonucleoprotein U-like protein 2

1

1

High-throughput

0.536

High

1243723

NEDD1
Protein NEDD1

1

1

High-throughput

0.536

High

1243753

BCLF1
Bcl-2-associated transcription factor 1

1

1

High-throughput

0.536

High

1243761

TR150
Thyroid hormone receptor-associated protein 3

1

1

High-throughput

0.536

High

1243744

TSG10
Testis-specific gene 10 protein

1

1

High-throughput

0.523

High

181222

NUP42
Nucleoporin NUP42

1

0

High-throughput

0.513

High

508618

TOP1
DNA topoisomerase 1

1

0

High-throughput

0.513

High

556640

CBR1
Carbonyl reductase [NADPH] 1

1

0

High-throughput

0.513

High

575792

VINC
Vinculin

1

0

High-throughput

0.513

High

801254

KI67
Proliferation marker protein Ki-67

1

0

High-throughput

0.513

High

887583

APC15
Anaphase-promoting complex subunit 15

1

0

High-throughput

0.513

High

945297

PRR3
Proline-rich protein 3

1

0

High-throughput

0.513

High

948820

HMGN5
High mobility group nucleosome-binding domain-containing protein 5

1

0

High-throughput

0.513

High

950831

ERH
Enhancer of rudimentary homolog

1

0

High-throughput

0.513

High

996780

SSRP1
FACT complex subunit SSRP1

1

0

High-throughput

0.513

High

1032250

CENPR
Centromere protein R

1

0

High-throughput

0.513

High

1050007

SCRIB
Protein scribble homolog

1

0

High-throughput

0.513

High

1052111

MAP7
Ensconsin

1

0

High-throughput

0.513

High

1084535

CPSF6
Cleavage and polyadenylation specificity factor subunit 6

1

0

High-throughput

0.513

High

1087273

H2B2E
Histone H2B type 2-E

1

0

High-throughput

0.513

High

1170119

FA83H
Protein FAM83H

1

0

High-throughput

0.513

High

1199072

MTA70
N6-adenosine-methyltransferase catalytic subunit

1

0

High-throughput

0.513

High

1243729

EZH1
Histone-lysine N-methyltransferase EZH1

1

0

High-throughput

0.513

High

1243735

PABP5
Polyadenylate-binding protein 5

1

0

High-throughput

0.513

High

1243749

CENPJ
Centromere protein J

1

0

High-throughput

0.513

High

1243755

DAXX
Death domain-associated protein 6

1

0

High-throughput

0.513

High

1043707

ASPP2
Apoptosis-stimulating of p53 protein 2

1

1

High-throughput

0.508

High

942813

SRPK2
SRSF protein kinase 2

1

3

High-throughput

0.501

High

443670

VIME
Vimentin

1

0

High-throughput

0.486

High

992104

B2CL1
Bcl-2-like protein 1

1

0

High-throughput

0.486

High

1036744

SQSTM
Sequestosome-1

1

0

High-throughput

0.486

High

1082883

CDC37
Hsp90 co-chaperone Cdc37

1

0

High-throughput

0.486

High

1243730

UFD1
Ubiquitin recognition factor in ER-associated degradation protein 1

1

0

High-throughput

0.486

High

1243757

NAGK
N-acetyl-D-glucosamine kinase

1

0

High-throughput

0.486

High

1173187

PAXI1
PAX-interacting protein 1

1

1

High-throughput

0.481

High

1243726

TOPB1
DNA topoisomerase 2-binding protein 1

1

1

Small-scale

0.481

High

175052

OGT1
UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit

1

0

High-throughput

0.480

High

395250

A4
Amyloid-beta precursor protein

1

0

High-throughput

0.480

High

851076

CASP5
Caspase-5

1

0

Small-scale

0.480

High

1243762

FBX7
F-box only protein 7

1

0

High-throughput

0.480

High

1243758

TASOR
Protein TASOR

1

0

Small-scale

0.479

High

308901

KI20A
Kinesin-like protein KIF20A

1

2

High-throughput

0.479

High

347370

MYC
Myc proto-oncogene protein

1

1

High-throughput

0.479

High

379630

MYCN
N-myc proto-oncogene protein

1

1

High-throughput

0.479

High

442321

RU17
U1 small nuclear ribonucleoprotein 70 kDa

1

1

High-throughput

0.479

High

794048

MATR3
Matrin-3

1

2

High-throughput

0.479

High

969868

KIF23
Kinesin-like protein KIF23

1

1

High-throughput

0.479

High

1061507

CUL7
Cullin-7

1

1

High-throughput

0.479

High

1085835

IF16
Gamma-interferon-inducible protein 16

1

1

High-throughput

0.479

High

1153878

IFIX
Pyrin and HIN domain-containing protein 1

1

1

High-throughput

0.479

High

1219343

CUL9
Cullin-9

1

1

High-throughput

0.479

High

1222474

SLX4
Structure-specific endonuclease subunit SLX4

1

1

High-throughput

0.479

High

1243722

NUP43
Nucleoporin Nup43

1

1

High-throughput

0.479

High

1243728

ESR2
Estrogen receptor beta

1

1

High-throughput

0.479

High

1243736

SNX27
Sorting nexin-27

1

1

High-throughput

0.479

High

1243738

RANB9
Ran-binding protein 9

1

1

High-throughput

0.479

High

1243754

NXF1
Nuclear RNA export factor 1

1

1

High-throughput

0.479

High

234253

PEPL
Periplakin

1

0

Small-scale

0.460

High

122887

MEN1
Menin

1

0

High-throughput

0.458

High

325814

LATS1
Serine/threonine-protein kinase LATS1

1

0

High-throughput

0.458

High

374562

RAF1
RAF proto-oncogene serine/threonine-protein kinase

1

0

High-throughput

0.458

High

453485

ROA1
Heterogeneous nuclear ribonucleoprotein A1

1

0

High-throughput

0.458

High

569886

CEBPB
CCAAT/enhancer-binding protein beta

1

0

High-throughput

0.458

High

718031

BMI1
Polycomb complex protein BMI-1

1

0

High-throughput

0.458

High

798950

GATA4
Transcription factor GATA-4

1

0

High-throughput

0.458

High

917620

H4
Histone H4

1

0

High-throughput

0.458

High

1054444

RBM39
RNA-binding protein 39

1

0

High-throughput

0.458

High

1066423

KIF14
Kinesin-like protein KIF14

1

0

High-throughput

0.458

High

1077420

ELAV1
ELAV-like protein 1

1

0

High-throughput

0.458

High

1174210

MOB2
MOB kinase activator 2

1

0

High-throughput

0.458

High

1220235

DHX40
Probable ATP-dependent RNA helicase DHX40

1

0

High-throughput

0.458

High

1221578

SMC5
Structural maintenance of chromosomes protein 5

1

0

High-throughput

0.458

High

1243724

DOT1L
Histone-lysine N-methyltransferase, H3 lysine-79 specific

1

0

High-throughput

0.458

High

1243733

CHM4C
Charged multivesicular body protein 4c

1

0

High-throughput

0.458

High

1243740

ANM1
Protein arginine N-methyltransferase 1

1

0

High-throughput

0.458

High

1243742

DDX23
Probable ATP-dependent RNA helicase DDX23

1

0

High-throughput

0.458

High

1243746

XRN2
5'-3' exoribonuclease 2

1

0

High-throughput

0.458

High

1243752

NLE1
Notchless protein homolog 1

1

0

High-throughput

0.458

High

1243756

ZRAN1
Ubiquitin thioesterase ZRANB1

1

0

High-throughput

0.458

High

833778

CLK1
Dual specificity protein kinase CLK1

1

2

High-throughput

0.457

High

70174

B2CML4
Apolipoprotein B mRNA editing enzyme catalytic polypeptide-like 3DE

1

2

High-throughput

0.445

High

904883

1433G
14-3-3 protein gamma

1

1

High-throughput

0.445

High

1145847

CP135
Centrosomal protein of 135 kDa

1

1

High-throughput

0.445

High

1243731

ABC3D
DNA dC->dU-editing enzyme APOBEC-3D

1

2

High-throughput

0.445

High

1243747

ATG5
Autophagy protein 5

1

0

Small-scale

0.438

High

1243737

ZN597
Zinc finger protein 597

4

0

High-throughput

0.360

High

230400

ZC3H1
Zinc finger C3H1 domain-containing protein

2

0

High-throughput

0.328

High

995402

LG3BP
Galectin-3-binding protein

2

0

High-throughput

0.328

High

1103167

KLH40
Kelch-like protein 40

2

0

High-throughput

0.328

High

1190495

P4HA3
Prolyl 4-hydroxylase subunit alpha-3

2

0

High-throughput

0.328

High

1102766

CCD57
Coiled-coil domain-containing protein 57

1

0

High-throughput

0.299

High

1127068

MTUS2
Microtubule-associated tumor suppressor candidate 2

1

0

High-throughput

0.299

High

1243741

SH3G3
Endophilin-A3

2

0

High-throughput

0.298

High

1072786

TOM20
Mitochondrial import receptor subunit TOM20 homolog

1

0

High-throughput

0.282

High

1243759

ITBP2
Integrin beta-1-binding protein 2

1

0

High-throughput

0.282

High

456175

IFI6
Interferon alpha-inducible protein 6

1

0

High-throughput

0.279

Low

483485

SAA1
Serum amyloid A-1 protein

1

0

High-throughput

0.279

Low

875875

MFAP4
Microfibril-associated glycoprotein 4

1

0

High-throughput

0.279

Low

1022737

MALL
MAL-like protein

1

0

High-throughput

0.279

Low

1023604

GAGE5
G antigen 5

1

0

High-throughput

0.279

Low

1138413

CP141
Cilia- and flagella-associated protein 141

1

0

High-throughput

0.279

Low

1204920

ZN677
Zinc finger protein 677

1

0

High-throughput

0.279

Low

1231392

CT197
Putative uncharacterized protein encoded by LINC02910

1

0

High-throughput

0.279

Low

1243732

RGMA
Repulsive guidance molecule A

1

0

High-throughput

0.279

Low

1243751

TM14B
Transmembrane protein 14B

1

0

High-throughput

0.279

Low

1243760

ANR50
Ankyrin repeat domain-containing protein 50

1

0

High-throughput

0.279

Low

1243727

SEPT8
Septin-8

1

0

High-throughput

0.265

Low

1170886

TRI67
Tripartite motif-containing protein 67

1

0

High-throughput

0.249

Low

1188578

PARPT
Protein mono-ADP-ribosyltransferase TIPARP

1

0

High-throughput

0.249

Low

1243748

PKHA4
Pleckstrin homology domain-containing family A member 4

1

0

High-throughput

0.249

Low


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Last updated: 15 Jul 2024