Interactor 1: NOT2 (P06100)
General negative regulator of transcription subunit 2 (cell division cycle protein 36)
Gene: CDC36

Interactor 2: NOT1 (P25655)
General negative regulator of transcription subunit 1 (Cell division cycle protein 39)
Gene: CDC39

Species: Saccharomyces cerevisiae S288C

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.96 1.00 0.980

The method score is based on:

Property Details
Experiments 12215531, 24121231, 9463387, 7926748, 19707589, 31851481, 16263706, 30948432, 35357307, 37968396, 20386698, 21669201, 18467557
Identification Methods two hybrid, tandem affinity purification, coimmunoprecipitation, pull down, affinity chromatography technology, cross-linking study, biochemical, dihydrofolate reductase reconstruction
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains NOT2_3_5_C~Not1
Common GO terms GO:0000288 - nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay
GO:0000289 - nuclear-transcribed mRNA poly(A) tail shortening
GO:0000749 - response to pheromone triggering conjugation with cellular fusion
GO:0005634 - nucleus
GO:0005737 - cytoplasm
and 4 others

more...

Homologous interactions 8

Homologous interactions

Color coding for hit scores

1 191
Sc

1 2108
+ Sc
+ Hs
+ Hs
+ Mm
+ Dm
+ Dm
+ Dm
+ Dm

Service provided by Combinatics, Japan

Last updated: 11Aug2025