Interactor 1: INHBA (P08476)
Inhibin beta A chain (Activin beta-A chain) (Erythroid differentiation protein) (EDF)
Gene: INHBA

Interactor 2: ACVR1 (Q04771)
Activin receptor type-1 (EC 2.7.11.30) (Activin receptor type I) (ACTR-I) (Activin receptor-like kinase 2) (ALK-2) (Serine/threonine-protein kinase receptor R1) (SKR1) (TGF-B superfamily receptor type I) (TSR-I)
Gene: ACVR1

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.38 1.00 0.618

The method score is based on:

Property Details
Experiments 8242742
Identification Methods affinity chromatography technology
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains Activin_recp~TGF_beta
Common GO terms GO:0017046 - peptide hormone binding
GO:0032924 - activin receptor signaling pathway
GO:0045893 - positive regulation of DNA-templated transcription
GO:0045944 - positive regulation of transcription by RNA polymerase II
GO:0060391 - positive regulation of SMAD protein signal transduction
and 1 others

more...

Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 426
Hs

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Last updated: 15 Jul 2024