HitPredict

Interactor 1: RU2B (P08579)
U2 small nuclear ribonucleoprotein B'' (U2 snRNP B'')
Gene: SNRPB2

Interactor 2: RSMN (P63162)
Small nuclear ribonucleoprotein-associated protein N (snRNP-N) (Sm protein D) (Sm-D) (Sm protein N) (Sm-N) (SmN) (Tissue-specific-splicing protein)
Gene: SNRPN

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.74	0.60	0.667

Property	Details
Experiments	28514442, 33961781, 17353931
Identification Methods	affinity chromatography technology, anti bait coimmunoprecipitation, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000398 - mRNA splicing, via spliceosome GO:0005654 - nucleoplasm GO:0005681 - spliceosomal complex GO:0005685 - U1 snRNP GO:0005686 - U2 snRNP and 1 others more... GO:0071013 - catalytic step 2 spliceosome
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 225 Hs			1 240
+	Hs
		441225 RU2B_HUMAN (1-225): 5.14e-51: 166: 100.00		RSMB_HUMAN (1-168): 1.09e-43: 148: 96.43
+	Hs
		446497 SNRPA_HUMAN (2-225): 2.91e-42: 146: 48.56		RSMB_HUMAN (1-168): 1.09e-43: 148: 96.43
+	Hs
		446577 SNRPA_HUMAN (2-225): 2.91e-42: 146: 48.56		RSMN_HUMAN (1-212): 4.46e-39: 137: 100.00
+	Sc
		766939 NAM8_YEAST (1-224): 5.12e-42: 150: 16.09		RSMB_YEAST (1-165): 2.64e-36: 128: 28.72
+	Dm
		795441 SNRPA_DROME (1-225): 1.52e-43: 147: 64.44		RSMB_DROME (1-204): 1.07e-29: 111: 58.82
+	Hs
		123833 SNRPA_HUMAN (2-225): 2.91e-42: 146: 48.56		SPT5H_HUMAN (100-228): 4.97e-25: 105: 17.69
+	Mm
		646096 TIA1_MOUSE (2-160): 4.64e-17: 80.5: 14.29		RSMB_MOUSE (1-168): 3.04e-45: 152: 96.43
+	Sc
		766913 MSL1_YEAST (7-91): 8.04e-27: 100: 30.59		RSMB_YEAST (1-165): 2.64e-36: 128: 28.72
+	Hs
		235690 HNRPQ_HUMAN (4-224): 8.43e-14: 71.6: 20.00		RSMB_HUMAN (1-168): 1.09e-43: 148: 96.43
+	Hs
		963541 TIAR_HUMAN (143-223): 1.61e-10: 61.7: 26.19		LFG1_HUMAN (117-223): 7.43e-09: 57.3: 19.63