Protein: NUCB2
Nucleobindin-2 (DNA-binding protein NEFA) (Epididymis secretory protein Li 109) (Gastric cancer antigen Zg4) (Prepronesfatin) [Cleaved into: Nesfatin-1]

Gene: NUCB2
Organism: Homo sapiens
Interactions: 148
UniProt ID: P80303

Gene Ontology (top 5):
GO:0001965 - G-protein alpha-subunit binding
GO:0003677 - DNA binding
GO:0005085 - guanyl-nucleotide exchange factor activity
GO:0005509 - calcium ion binding
GO:0005615 - extracellular space

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

822796

TNNI2
Troponin I, fast skeletal muscle

2

0

High-throughput

0.770

High

945902

TREM2
Triggering receptor expressed on myeloid cells 2

1

0

High-throughput

0.656

High

945915

COL10
Collectin-10

3

0

High-throughput

0.638

High

566746

JUNB
Transcription factor JunB

2

1

High-throughput

0.628

High

216211

CALU
Calumenin

1

2

High-throughput

0.618

High

531791

PDIA4
Protein disulfide-isomerase A4

1

3

High-throughput

0.618

High

945857

DJC10
DnaJ homolog subfamily C member 10

1

5

High-throughput

0.618

High

945833

NUCB1
Nucleobindin-1

2

0

High-throughput

0.585

High

945876

CALR3
Calreticulin-3

2

3

High-throughput

0.584

High

945843

RCN1
Reticulocalbin-1

1

2

High-throughput

0.575

High

945875

SCYL1
N-terminal kinase-like protein

1

1

High-throughput

0.575

High

945882

ERP44
Endoplasmic reticulum resident protein 44

1

4

High-throughput

0.575

High

945880

NECD
Necdin

1

1

Small-scale

0.573

High

501971

BIP
Endoplasmic reticulum chaperone BiP

2

1

High-throughput

0.571

High

945903

VAPA
Vesicle-associated membrane protein-associated protein A

2

1

High-throughput

0.571

High

532101

P4HA1
Prolyl 4-hydroxylase subunit alpha-1

1

0

High-throughput

0.546

High

821987

KC1A
Casein kinase I isoform alpha

1

0

High-throughput

0.546

High

945866

MCFD2
Multiple coagulation factor deficiency protein 2

1

0

High-throughput

0.546

High

401832

JUN
Transcription factor Jun

1

3

High-throughput

0.536

High

862901

CEBPG
CCAAT/enhancer-binding protein gamma

1

3

High-throughput

0.536

High

863403

COPA
Coatomer subunit alpha

1

1

High-throughput

0.536

High

945861

FNDC5
Fibronectin type III domain-containing protein 5

1

2

High-throughput

0.536

High

945891

MANS1
MANSC domain-containing protein 1

1

1

High-throughput

0.536

High

945908

PA2GD
Group IID secretory phospholipase A2

1

1

High-throughput

0.536

High

945909

ANGP4
Angiopoietin-4

1

1

High-throughput

0.536

High

431207

CATB
Cathepsin B

1

1

High-throughput

0.515

High

648720

DPP4
Dipeptidyl peptidase 4

1

1

High-throughput

0.515

High

945890

TMX1
Thioredoxin-related transmembrane protein 1

1

5

High-throughput

0.514

High

149607

COPE
Coatomer subunit epsilon

1

0

High-throughput

0.513

High

945837

CUL2
Cullin-2

1

0

High-throughput

0.513

High

945870

YIPF5
Protein YIPF5

1

0

High-throughput

0.513

High

788181

CASP3
Caspase-3

1

5

Small-scale

0.501

High

876937

CASP7
Caspase-7

1

5

Small-scale

0.501

High

877013

CASP6
Caspase-6

1

5

Small-scale

0.501

High

945839

CASP8
Caspase-8

1

5

Small-scale

0.501

High

364242

TFR1
Transferrin receptor protein 1

1

0

High-throughput

0.493

High

637238

CATS
Cathepsin S

1

0

High-throughput

0.493

High

945888

CSTL1
Cystatin-like 1

1

1

High-throughput

0.489

High

945901

ERAP1
Endoplasmic reticulum aminopeptidase 1

1

0

Small-scale

0.484

High

297741

MICA2
[F-actin]-monooxygenase MICAL2

1

0

High-throughput

0.481

High

162625

XPO1
Exportin-1

1

1

High-throughput

0.481

High

444713

GNAI3
Guanine nucleotide-binding protein G(i) subunit alpha-3

1

7

High-throughput

0.481

High

926566

GNAS2
Guanine nucleotide-binding protein G(s) subunit alpha isoforms short

1

7

High-throughput

0.481

High

945848

AR13B
ADP-ribosylation factor-like protein 13B

1

1

High-throughput

0.481

High

205265

TGON2
Trans-Golgi network integral membrane protein 2

1

1

High-throughput

0.479

High

569578

CEBPB
CCAAT/enhancer-binding protein beta

1

1

High-throughput

0.479

High

674389

UFO
Tyrosine-protein kinase receptor UFO

1

4

High-throughput

0.479

High

890099

SC61B
Protein transport protein Sec61 subunit beta

1

1

High-throughput

0.479

High

945836

DNJC3
DnaJ homolog subfamily C member 3

1

3

High-throughput

0.479

High

945847

TECT1
Tectonic-1

1

1

High-throughput

0.479

High

945850

EPHAA
Ephrin type-A receptor 10

1

4

High-throughput

0.479

High

945854

SYNE3
Nesprin-3

1

1

High-throughput

0.479

High

945872

LRC59
Leucine-rich repeat-containing protein 59

1

1

High-throughput

0.479

High

945877

SNX27
Sorting nexin-27

1

1

High-throughput

0.479

High

945895

T106B
Transmembrane protein 106B

1

1

High-throughput

0.479

High

945898

DJB12
DnaJ homolog subfamily B member 12

1

3

High-throughput

0.479

High

945905

DNJB9
DnaJ homolog subfamily B member 9

1

5

High-throughput

0.479

High

945907

ZRAN1
Ubiquitin thioesterase ZRANB1

1

1

High-throughput

0.479

High

945914

BIG2
Brefeldin A-inhibited guanine nucleotide-exchange protein 2

1

1

Small-scale

0.479

High

183234

FFAR2
Free fatty acid receptor 2

1

0

High-throughput

0.460

High

676535

CTR1
High affinity cationic amino acid transporter 1

1

0

High-throughput

0.460

High

945834

ASPH
Aspartyl/asparaginyl beta-hydroxylase

1

0

High-throughput

0.460

High

434172

RET
Proto-oncogene tyrosine-protein kinase receptor Ret

1

0

High-throughput

0.458

High

749369

BRCA1
Breast cancer type 1 susceptibility protein

1

0

High-throughput

0.458

High

813377

CAPZB
F-actin-capping protein subunit beta

1

0

High-throughput

0.458

High

821842

HSP13
Heat shock 70 kDa protein 13

1

0

High-throughput

0.458

High

945852

CDC73
Parafibromin

1

0

High-throughput

0.458

High

945869

AKAP1
A-kinase anchor protein 1, mitochondrial

1

0

High-throughput

0.458

High

945906

DJB11
DnaJ homolog subfamily B member 11

1

0

High-throughput

0.458

High

48330

ESYT2
Extended synaptotagmin-2

1

1

High-throughput

0.445

High

99783

F5H6I7
Atlastin GTPase 3

1

2

High-throughput

0.445

High

258918

RTN2
Reticulon-2

1

2

High-throughput

0.445

High

307020

RTN3
Reticulon-3

1

2

High-throughput

0.445

High

310601

VAPB
Vesicle-associated membrane protein-associated protein B/C

1

1

High-throughput

0.445

High

653555

CALR
Calreticulin

1

3

High-throughput

0.445

High

654258

CALX
Calnexin

1

3

High-throughput

0.445

High

725417

COPB2
Coatomer subunit beta'

1

1

High-throughput

0.445

High

833199

TMEDA
Transmembrane emp24 domain-containing protein 10

1

2

High-throughput

0.445

High

945844

TMED2
Transmembrane emp24 domain-containing protein 2

1

2

High-throughput

0.445

High

945849

DHB12
Very-long-chain 3-oxoacyl-CoA reductase

1

2

High-throughput

0.445

High

945858

PACE1
Protein-associating with the carboxyl-terminal domain of ezrin

1

1

High-throughput

0.445

High

945862

DHB11
Estradiol 17-beta-dehydrogenase 11

1

2

High-throughput

0.445

High

945865

ATLA2
Atlastin-2

1

2

High-throughput

0.445

High

945868

ATLA1
Atlastin-1

1

2

High-throughput

0.445

High

945883

ESYT1
Extended synaptotagmin-1

1

1

High-throughput

0.445

High

945893

RTN4
Reticulon-4

1

2

High-throughput

0.445

High

945899

PSD3
PH and SEC7 domain-containing protein 3

1

1

High-throughput

0.445

High

945904

COPG2
Coatomer subunit gamma-2

1

1

High-throughput

0.445

High

945911

TMED5
Transmembrane emp24 domain-containing protein 5

1

2

High-throughput

0.445

High

945913

COPG1
Coatomer subunit gamma-1

1

1

High-throughput

0.445

High

945851

TECT3
Tectonic-3

1

1

High-throughput

0.437

High

945855

TRI67
Tripartite motif-containing protein 67

1

1

High-throughput

0.437

High

58070

NBAS
NBAS subunit of NRZ tethering complex

1

0

High-throughput

0.426

High

199318

ZW10
Centromere/kinetochore protein zw10 homolog

1

0

High-throughput

0.426

High

201003

VIP2
Inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 2

1

0

High-throughput

0.426

High

202872

EMC8
ER membrane protein complex subunit 8

1

0

High-throughput

0.426

High

266143

ERLN1
Erlin-1

1

0

High-throughput

0.426

High

277048

STAM2
Signal transducing adapter molecule 2

1

0

High-throughput

0.426

High

335402

NB5R3
NADH-cytochrome b5 reductase 3

1

0

High-throughput

0.426

High

432655

HNRPC
Heterogeneous nuclear ribonucleoproteins C1/C2

1

0

High-throughput

0.426

High

818918

COPD
Coatomer subunit delta

1

0

High-throughput

0.426

High

827781

AL7A1
Alpha-aminoadipic semialdehyde dehydrogenase

1

0

High-throughput

0.426

High

847248

SSRD
Translocon-associated protein subunit delta

1

0

High-throughput

0.426

High

847441

BAP31
B-cell receptor-associated protein 31

1

0

High-throughput

0.426

High

863199

COPB
Coatomer subunit beta

1

0

High-throughput

0.426

High

902295

COPZ1
Coatomer subunit zeta-1

1

0

High-throughput

0.426

High

923951

RS27A
Ubiquitin-ribosomal protein eS31 fusion protein

1

0

High-throughput

0.426

High

945831

ARF5
ADP-ribosylation factor 5

1

0

High-throughput

0.426

High

945832

REEP5
Receptor expression-enhancing protein 5

1

0

High-throughput

0.426

High

945835

PRDX4
Peroxiredoxin-4

1

0

High-throughput

0.426

High

945838

GANAB
Neutral alpha-glucosidase AB

1

0

High-throughput

0.426

High

945840

EMC2
ER membrane protein complex subunit 2

1

0

High-throughput

0.426

High

945841

AR6P1
ADP-ribosylation factor-like protein 6-interacting protein 1

1

0

High-throughput

0.426

High

945842

RB3GP
Rab3 GTPase-activating protein catalytic subunit

1

0

High-throughput

0.426

High

945845

DHC24
Delta(24)-sterol reductase

1

0

High-throughput

0.426

High

945846

NSDHL
Sterol-4-alpha-carboxylate 3-dehydrogenase, decarboxylating

1

0

High-throughput

0.426

High

945853

LCLT1
Lysocardiolipin acyltransferase 1

1

0

High-throughput

0.426

High

945856

UB2R2
Ubiquitin-conjugating enzyme E2 R2

1

0

High-throughput

0.426

High

945859

CISD2
CDGSH iron-sulfur domain-containing protein 2

1

0

High-throughput

0.426

High

945864

VP37A
Vacuolar protein sorting-associated protein 37A

1

0

High-throughput

0.426

High

945867

SCFD1
Sec1 family domain-containing protein 1

1

0

High-throughput

0.426

High

945871

ERGI1
Endoplasmic reticulum-Golgi intermediate compartment protein 1

1

0

High-throughput

0.426

High

945873

ASTRA
Protein Aster-A

1

0

High-throughput

0.426

High

945878

NUDC1
NudC domain-containing protein 1

1

0

High-throughput

0.426

High

945884

NDC1
Nucleoporin NDC1

1

0

High-throughput

0.426

High

945885

WDR11
WD repeat-containing protein 11

1

0

High-throughput

0.426

High

945886

LNP
Endoplasmic reticulum junction formation protein lunapark

1

0

High-throughput

0.426

High

945887

RGAP1
Rac GTPase-activating protein 1

1

0

High-throughput

0.426

High

945889

RBGPR
Rab3 GTPase-activating protein non-catalytic subunit

1

0

High-throughput

0.426

High

945894

SAC1
Phosphatidylinositol-3-phosphatase SAC1

1

0

High-throughput

0.426

High

945900

TECR
Very-long-chain enoyl-CoA reductase

1

0

High-throughput

0.426

High

945912

SERC
Phosphoserine aminotransferase

1

0

High-throughput

0.426

High

945881

PXL2A
Peroxiredoxin-like 2A

1

1

High-throughput

0.407

High

945910

DHRS7
Dehydrogenase/reductase SDR family member 7

1

1

High-throughput

0.407

High

887164

Z280A
Zinc finger protein 280A

2

0

High-throughput

0.324

High

622939

GA45A
Growth arrest and DNA damage-inducible protein GADD45 alpha

1

0

High-throughput

0.299

High

905469

TIM10
Mitochondrial import inner membrane translocase subunit Tim10

1

0

High-throughput

0.279

Low

265862

NR1I2
Nuclear receptor subfamily 1 group I member 2

1

0

High-throughput

0.251

Low

830519

STAR
Steroidogenic acute regulatory protein, mitochondrial

1

0

Small-scale

0.251

Low

945874

SMRD1
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 1

1

0

High-throughput

0.251

Low

133438

NOP56
Nucleolar protein 56

1

0

High-throughput

0.249

Low

945879

IMP2L
Mitochondrial inner membrane protease subunit 2

1

0

High-throughput

0.249

Low

50130

HACL2
2-hydroxyacyl-CoA lyase 2

1

0

High-throughput

0.232

Low

945860

EMC1
ER membrane protein complex subunit 1

1

0

High-throughput

0.232

Low

945863

PDZD8
PDZ domain-containing protein 8

1

0

High-throughput

0.232

Low

945892

APMAP
Adipocyte plasma membrane-associated protein

1

0

High-throughput

0.232

Low

945896

TM38B
Trimeric intracellular cation channel type B

1

0

High-throughput

0.232

Low

945897

GPTC2
G patch domain-containing protein 2

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 15 Jul 2024