Interactor 1: HCK (P08631)
Tyrosine-protein kinase HCK (EC 2.7.10.2) (Hematopoietic cell kinase) (Hemopoietic cell kinase) (p59-HCK/p60-HCK) (p59Hck) (p61Hck)
Gene: HCK

Interactor 2: RPGF1 (Q13905)
Rap guanine nucleotide exchange factor 1 (CRK SH3-binding GNRP) (Guanine nucleotide-releasing factor 2) (Protein C3G)
Gene: RAPGEF1

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.54 0.60 0.573

The method score is based on:

Property Details
Experiments 14551197
Identification Methods pull down, two hybrid, affinity chromatography technology
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005829 - cytosol
GO:0005886 - plasma membrane
GO:0007169 - cell surface receptor protein tyrosine kinase signaling pathway
GO:0043231 - intracellular membrane-bounded organelle
Homologous interactions 14

Homologous interactions

Color coding for hit scores

1 526
Hs

1 1077
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+ Dm
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024