Protein: RB
Retinoblastoma-associated protein (p110-RB1) (pRb) (Rb) (pp105)

Gene: RB, Rb1
Organism: Mus musculus
Interactions: 43
UniProt ID: P13405

Gene Ontology (top 5):
GO:0000082 - G1/S transition of mitotic cell cycle
GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0001558 - regulation of cell growth
GO:0001894 - tissue homeostasis
GO:0002062 - chondrocyte differentiation

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

561645

E2F1
Transcription factor E2F1

3

20

Small-scale

0.829

High

561629

E2F2
Transcription factor E2F2

1

20

Small-scale

0.691

High

561623

CDK4
Cyclin-dependent kinase 4

3

19

Small-scale

0.655

High

204561

E2F3
Transcription factor E2F3

1

20

Small-scale

0.618

High

561636

CDK2
Cyclin-dependent kinase 2

2

11

Small-scale

0.602

High

561620

CCND1
G1/S-specific cyclin-D1

2

20

Small-scale

0.595

High

561637

CEBPD
CCAAT/enhancer-binding protein delta

2

9

Small-scale

0.594

High

148640

HDAC1
Histone deacetylase 1

2

12

Small-scale

0.584

High

561658

PSD10
26S proteasome non-ATPase regulatory subunit 10

2

2

Small-scale

0.584

High

561621

CEBPB
CCAAT/enhancer-binding protein beta

1

10

Small-scale

0.578

High

561653

E2F4
Transcription factor E2F4

1

20

High-throughput

0.575

High

561640

SMCA4
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 4

1

5

Small-scale

0.552

High

561634

HMGB1
High mobility group protein B1

1

3

Small-scale

0.536

High

561633

PP1G
Serine/threonine-protein phosphatase PP1-gamma catalytic subunit

1

5

High-throughput

0.534

High

561656

IFI2
Interferon-activable protein 202

1

1

Small-scale

0.534

High

561619

PAX3
Paired box protein Pax-3

1

5

Small-scale

0.527

High

561644

VSX2
Visual system homeobox 2

1

2

Small-scale

0.527

High

561651

RBAK
RB-associated KRAB zinc finger protein

1

1

Small-scale

0.527

High

561626

HMGA2
High mobility group protein HMGI-C

1

1

Small-scale

0.515

High

561639

Q155P7
LEK1

1

2

Small-scale

0.515

High

561628

CEBPA
CCAAT/enhancer-binding protein alpha

1

9

Small-scale

0.501

High

561641

KMT5B
Histone-lysine N-methyltransferase KMT5B

1

5

Small-scale

0.501

High

561648

CDK6
Cyclin-dependent kinase 6

1

20

Small-scale

0.501

High

561649

KMT5C
Histone-lysine N-methyltransferase KMT5C

1

5

Small-scale

0.501

High

561654

CDK9
Cyclin-dependent kinase 9

1

17

Small-scale

0.501

High

561618

GATA1
Erythroid transcription factor

1

1

Small-scale

0.500

High

561625

ID2
DNA-binding protein inhibitor ID-2

1

3

High-throughput

0.481

High

561638

RUNX2
Runt-related transcription factor 2

1

2

High-throughput

0.481

High

561622

CCND3
G1/S-specific cyclin-D3

1

19

Small-scale

0.479

High

561624

PAX2
Paired box protein Pax-2

1

5

Small-scale

0.479

High

561627

PDX1
Pancreas/duodenum homeobox protein 1

1

1

Small-scale

0.479

High

561630

MO4L1
Mortality factor 4-like protein 1

1

2

Small-scale

0.479

High

561631

PP1A
Serine/threonine-protein phosphatase PP1-alpha catalytic subunit

1

3

High-throughput

0.479

High

561632

PP1B
Serine/threonine-protein phosphatase PP1-beta catalytic subunit

1

5

High-throughput

0.479

High

561635

KPCB
Protein kinase C beta type

1

1

Small-scale

0.479

High

561643

NDF1
Neurogenic differentiation factor 1

1

6

Small-scale

0.479

High

561646

JARD2
Protein Jumonji

1

4

Small-scale

0.479

High

561647

CCNC
Cyclin-C

1

12

Small-scale

0.479

High

561650

DGKZ
Diacylglycerol kinase zeta

1

5

Small-scale

0.479

High

561655

MOFA1
MORF4 family-associated protein 1

1

2

Small-scale

0.479

High

561657

ANM2
Protein arginine N-methyltransferase 2

1

2

Small-scale

0.479

High

561642

Q3UKX1
Protein arginine N-methyltransferase 2

1

2

Small-scale

0.437

High

561652

TTC23
Tetratricopeptide repeat protein 23

1

0

High-throughput

0.249

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025