HitPredict

Interactor 1: NFIC (P08651)
Nuclear factor 1 C-type (NF1-C) (Nuclear factor 1/C) (CCAAT-box-binding transcription factor) (CTF) (Nuclear factor I/C) (NF-I/C) (NFI-C) (TGGCA-binding protein)
Gene: NFIC

Interactor 2: NCOA3 (Q9Y6Q9)
Nuclear receptor coactivator 3 (NCoA-3) (EC 2.3.1.48) (ACTR) (Amplified in breast cancer 1 protein) (AIB-1) (CBP-interacting protein) (pCIP) (Class E basic helix-loop-helix protein 42) (bHLHe42) (Receptor-associated coactivator 3) (RAC-3) (Steroid receptor coactivator protein 3) (SRC-3) (Thyroid hormone receptor activator molecule 1) (TRAM-1)
Gene: NCOA3

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	35140242
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000785 - chromatin GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0045944 - positive regulation of transcription by RNA polymerase II
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 508 Hs			1 1424
+	Hs
		1018288 NFIA_HUMAN (2-508): 1.69e-133: 398: 59.20		NCOA3_HUMAN (1-1424): 3.11e-164: 533: 100.00
+	Hs
		135182 NFIB_HUMAN (1-423): 2.4e-128: 381: 63.47		NCOA3_HUMAN (1-1424): 3.11e-164: 533: 100.00
+	Hs
		1018226 NFIA_HUMAN (2-508): 1.69e-133: 398: 59.20		NCOA2_HUMAN (1-1422): 5.82e-99: 350: 38.89
+	Hs
		1060330 NFIX_HUMAN (2-507): 2.17e-156: 456: 56.73		KMT2C_HUMAN (471-1383): 2.87e-11: 70.9: 12.87
+	Hs
		135133 NFIB_HUMAN (1-423): 2.4e-128: 381: 63.47		KMT2C_HUMAN (471-1383): 2.87e-11: 70.9: 12.87
+	Hs
		625014 RPB1_HUMAN (374-496): 2.39e-09: 62.2: 20.33		EPAS1_HUMAN (12-878): 3.88e-100: 343: 13.27