HitPredict

Interactor 1: VIME (P08670)
Vimentin
Gene: VIM

Interactor 2: IDE (P14735)
Insulin-degrading enzyme (EC 3.4.24.56) (Abeta-degrading protease) (Insulin protease) (Insulinase) (Insulysin)
Gene: IDE

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	0.60	0.628

Property	Details
Experiments	28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005777 - peroxisome GO:0005829 - cytosol GO:0070062 - extracellular exosome
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 466 Hs			1 1019
+	Hs
		535317 GFAP_HUMAN (80-465): 2.56e-132: 390: 61.40		IDE_HUMAN (1-1019): 0: 1084: 100.00
+	Hs
		539799 AINX_HUMAN (82-422): 6.14e-97: 302: 54.91		IDE_HUMAN (1-1019): 0: 1084: 100.00
+	Hs
		422141 NFL_HUMAN (82-413): 4.58e-87: 278: 51.80		IDE_HUMAN (1-1019): 0: 1084: 100.00
+	Hs
		422339 NFM_HUMAN (9-412): 5.26e-84: 278: 46.44		IDE_HUMAN (1-1019): 0: 1084: 100.00
+	Hs
		264832 DESM_HUMAN (9-465): 6.68e-138: 406: 62.20		MPPB_HUMAN (49-493): 2.22e-113: 360: 16.81
+	Hs
		569074 DESM_HUMAN (9-465): 6.68e-138: 406: 62.20		MPPA_HUMAN (6-482): 9.37e-106: 341: 14.54
+	Hs
		1055207 KRT81_HUMAN (4-418): 4.08e-91: 287: 31.74		PREP_HUMAN (91-965): 1.14e-133: 431: 13.57
+	Hs
		213957 KRT86_HUMAN (4-418): 5.74e-90: 284: 31.74		PREP_HUMAN (91-965): 1.14e-133: 431: 13.57
+	Hs
		213916 KRT86_HUMAN (4-418): 5.74e-90: 284: 31.74		MPPB_HUMAN (49-493): 2.22e-113: 360: 16.81
+	Hs
		264804 K2C75_HUMAN (6-422): 9.96e-85: 272: 32.51		MPPB_HUMAN (49-493): 2.22e-113: 360: 16.81
+	Hs
		213941 KRT86_HUMAN (4-418): 5.74e-90: 284: 31.74		MPPA_HUMAN (6-482): 9.37e-106: 341: 14.54