Protein: PI51C
Phosphatidylinositol 4-phosphate 5-kinase type-1 gamma (PIP5K1gamma) (PtdIns(4)P-5-kinase 1 gamma) (EC 2.7.1.68) (Type I phosphatidylinositol 4-phosphate 5-kinase gamma)

Gene: PI51C, PIP5K1C
Organism: Homo sapiens
Interactions: 52
UniProt ID: O60331

Gene Ontology (top 5):
GO:0001891 - phagocytic cup
GO:0001931 - uropod
GO:0005524 - ATP binding
GO:0005654 - nucleoplasm
GO:0005829 - cytosol

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

245812

PI51A
Phosphatidylinositol 4-phosphate 5-kinase type-1 alpha

3

14

High-throughput

0.839

High

245818

TLN1
Talin-1

6

6

Small-scale

0.726

High

245794

PGTB2
Geranylgeranyl transferase type-2 subunit beta

3

2

High-throughput

0.667

High

245778

CADH1
Cadherin-1

3

2

Small-scale

0.646

High

245820

SNX5
Sorting nexin-5

2

1

Small-scale

0.620

High

245803

PI5L1
Phosphatidylinositol 4-phosphate 5-kinase-like protein 1

1

14

Small-scale

0.618

High

245792

IQGA1
Ras GTPase-activating-like protein IQGAP1

1

1

Small-scale

0.586

High

245795

ARF6
ADP-ribosylation factor 6

2

4

Small-scale

0.584

High

245815

SMUF1
E3 ubiquitin-protein ligase SMURF1

1

6

Small-scale

0.578

High

245793

PI42A
Phosphatidylinositol 5-phosphate 4-kinase type-2 alpha

1

14

High-throughput

0.575

High

245808

ARHG1
Rho guanine nucleotide exchange factor 1

2

3

High-throughput

0.571

High

245779

SRC
Proto-oncogene tyrosine-protein kinase Src

1

1

Small-scale

0.561

High

245791

NEDD4
E3 ubiquitin-protein ligase NEDD4

1

6

Small-scale

0.561

High

245819

TLN2
Talin-2

1

9

Small-scale

0.561

High

245805

LAP4B
Lysosomal-associated transmembrane protein 4B

1

0

Small-scale

0.537

High

245772

SNX4
Sorting nexin-4

1

1

High-throughput

0.536

High

245806

PGBD5
PiggyBac transposable element-derived protein 5

1

1

High-throughput

0.536

High

245782

VDAC1
Non-selective voltage-gated ion channel VDAC1

1

0

High-throughput

0.513

High

245775

CDK1
Cyclin-dependent kinase 1

1

6

Small-scale

0.501

High

245784

AKT1
RAC-alpha serine/threonine-protein kinase

1

3

Small-scale

0.501

High

245785

AKT2
RAC-beta serine/threonine-protein kinase

1

3

Small-scale

0.501

High

245799

PKD1
Polycystin-1

1

4

Small-scale

0.501

High

245800

CDK5
Cyclin-dependent kinase 5

1

6

Small-scale

0.501

High

245788

SYUA
Alpha-synuclein

1

1

High-throughput

0.481

High

245774

ITB1
Integrin beta-1

1

0

Small-scale

0.480

High

245771

AP2A2
AP-2 complex subunit alpha-2

1

3

Small-scale

0.479

High

245773

P53
Cellular tumor antigen p53

1

1

High-throughput

0.479

High

245776

UBC
Polyubiquitin-C [Cleaved into: Ubiquitin]

1

3

Small-scale

0.479

High

245780

VAV
Proto-oncogene vav

1

2

High-throughput

0.479

High

245781

CADH2
Cadherin-2

1

2

Small-scale

0.479

High

245786

CADH5
Cadherin-5

1

2

Small-scale

0.479

High

245790

MUC18
Cell surface glycoprotein MUC18

1

1

High-throughput

0.479

High

245796

RAC1
Ras-related C3 botulinum toxin substrate 1

1

9

High-throughput

0.479

High

245797

AP2B1
AP-2 complex subunit beta

1

5

Small-scale

0.479

High

245802

LARP7
La-related protein 7

1

3

High-throughput

0.479

High

245813

RHOJ
Rho-related GTP-binding protein RhoJ

1

12

High-throughput

0.479

High

245814

RHOF
Rho-related GTP-binding protein RhoF

1

12

High-throughput

0.479

High

245816

ZRAN1
Ubiquitin thioesterase ZRANB1

1

6

High-throughput

0.479

High

245770

CTND1
Catenin delta-1

1

0

Small-scale

0.458

High

245783

DPP4
Dipeptidyl peptidase 4

1

0

High-throughput

0.458

High

245804

BAKOR
Beclin 1-associated autophagy-related key regulator

1

0

Small-scale

0.458

High

245777

TAU
Microtubule-associated protein tau

1

5

High-throughput

0.445

High

245789

PK3CA
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform

1

1

High-throughput

0.445

High

245801

RNPS1
RNA-binding protein with serine-rich domain 1

1

4

High-throughput

0.445

High

245807

IN80E
INO80 complex subunit E

1

1

High-throughput

0.445

High

245809

Q96D37
VAV1 protein

1

2

High-throughput

0.445

High

245811

EAF1
ELL-associated factor 1

1

4

High-throughput

0.445

High

245817

FBX3
F-box only protein 3

1

1

High-throughput

0.445

High

104917

APRIO
Alternative prion protein

1

1

High-throughput

0.437

High

245798

PRR3
Proline-rich protein 3

1

2

High-throughput

0.407

High

245787

SOAT1
Sterol O-acyltransferase 1

1

0

High-throughput

0.279

Low

245810

COQ2
4-hydroxybenzoate polyprenyltransferase, mitochondrial

1

0

High-throughput

0.279

Low


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Last updated: 11Aug2025