HitPredict

Interactor 1: K1C19 (P08727)
Keratin, type I cytoskeletal 19 (Cytokeratin-19) (CK-19) (Keratin-19) (K19)
Gene: KRT19

Interactor 2: AMOL2 (Q9Y2J4)
Angiomotin-like protein 2 (Leman coiled-coil protein) (LCCP)
Gene: AMOTL2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.54	0.60	0.573

Property	Details
Experiments	25416956
Identification Methods	two hybrid, two hybrid prey pooling approach, two hybrid array, validated two hybrid
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0005886 - plasma membrane
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 400 Hs			1 779
+	Hs
		444383 K1C19_HUMAN (1-400): 3.13e-157: 450: 100.00		AMOT_HUMAN (1-740): 2.7e-70: 252: 32.32
+	Hs
		359364 K1C14_HUMAN (78-391): 5.81e-143: 416: 70.38		AMOT_HUMAN (1-740): 2.7e-70: 252: 32.32
+	Hs
		580033 K1C15_HUMAN (79-388): 4.51e-142: 414: 71.70		AMOT_HUMAN (1-740): 2.7e-70: 252: 32.32
+	Hs
		580125 K1C15_HUMAN (79-388): 4.51e-142: 414: 71.70		AMOL2_HUMAN (1-779): 1.36e-71: 251: 100.00
+	Hs
		1071191 K1H1_HUMAN (35-397): 1.31e-141: 411: 50.55		AMOT_HUMAN (1-740): 2.7e-70: 252: 32.32
+	Hs
		1071452 K1H1_HUMAN (35-397): 1.31e-141: 411: 50.55		AMOL2_HUMAN (1-779): 1.36e-71: 251: 100.00
+	Hs
		445063 K1C16_HUMAN (76-397): 5.27e-140: 409: 70.19		AMOT_HUMAN (1-740): 2.7e-70: 252: 32.32
+	Hs
		531526 K1C13_HUMAN (74-388): 7.1e-141: 410: 70.57		AMOL2_HUMAN (1-779): 1.36e-71: 251: 100.00
+	Hs
		57664 K1C19_HUMAN (1-400): 3.13e-157: 450: 100.00		A2BDD9_HUMAN (293-740): 2.1e-43: 169: 48.73
+	Hs
		444418 K1C19_HUMAN (1-400): 3.13e-157: 450: 100.00		AMOL1_HUMAN (1-766): 4.56e-42: 167: 40.22
+	Hs
		57663 K1C14_HUMAN (78-391): 5.81e-143: 416: 70.38		A2BDD9_HUMAN (293-740): 2.1e-43: 169: 48.73
+	Hs
		57666 K1C15_HUMAN (79-388): 4.51e-142: 414: 71.70		A2BDD9_HUMAN (293-740): 2.1e-43: 169: 48.73
+	Hs
		57680 K1H1_HUMAN (35-397): 1.31e-141: 411: 50.55		A2BDD9_HUMAN (293-740): 2.1e-43: 169: 48.73
+	Hs
		57665 K1C16_HUMAN (76-397): 5.27e-140: 409: 70.19		A2BDD9_HUMAN (293-740): 2.1e-43: 169: 48.73
+	Hs
		444487 K1C19_HUMAN (1-400): 3.13e-157: 450: 100.00		MYO5C_HUMAN (85-502): 3.91e-13: 75.5: 11.37
+	Hs
		444307 K1C19_HUMAN (1-400): 3.13e-157: 450: 100.00		DESP_HUMAN (16-454): 7.49e-11: 68.1: 12.02
+	Hs
		444372 K1C19_HUMAN (1-400): 3.13e-157: 450: 100.00		PLEC_HUMAN (191-769): 1.21e-09: 64.3: 9.88
+	Hs
		522534 K1C13_HUMAN (74-388): 7.1e-141: 410: 70.57		MYH1_HUMAN (348-778): 4.72e-15: 82: 10.88
+	Hs
		359355 K1C14_HUMAN (78-391): 5.81e-143: 416: 70.38		PLEC_HUMAN (191-769): 1.21e-09: 64.3: 9.88
+	Hs
		445052 K1C16_HUMAN (76-397): 5.27e-140: 409: 70.19		PLEC_HUMAN (191-769): 1.21e-09: 64.3: 9.88