HitPredict

Interactor 1: RSSA (P08865)
Small ribosomal subunit protein uS2 (37 kDa laminin receptor precursor) (37LRP) (37/67 kDa laminin receptor) (LRP/LR) (40S ribosomal protein SA) (67 kDa laminin receptor) (67LR) (Colon carcinoma laminin-binding protein) (Laminin receptor 1) (LamR) (Laminin-binding protein precursor p40) (LBP/p40) (Multidrug resistance-associated protein MGr1-Ag) (NEM/1CHD4)
Gene: RPSA

Interactor 2: SMUF2 (Q9HAU4)
E3 ubiquitin-protein ligase SMURF2 (hSMURF2) (EC 2.3.2.26) (HECT-type E3 ubiquitin transferase SMURF2) (SMAD ubiquitination regulatory factor 2) (SMAD-specific E3 ubiquitin-protein ligase 2)
Gene: SMURF2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0005886 - plasma membrane
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1 295 Hs			1 748
+	Hs
		445314 RSSA_HUMAN (1-295): 2.16e-153: 432: 100.00		NEDD4_HUMAN (104-746): 0: 628: 38.73
+	Sc
		700429 RSSA1_YEAST (5-254): 1.72e-100: 296: 52.59		RSP5_YEAST (11-748): 0: 638: 34.33
+	Sc
		804834 RSSA2_YEAST (5-254): 1.56e-100: 296: 52.59		TOM1_YEAST (325-747): 1.36e-156: 505: 40.47
+	Hs
		125104 RSSA_HUMAN (1-295): 2.16e-153: 432: 100.00		WWP2_HUMAN (1-416): 7.64e-26: 116: 17.39
+	Hs
		445528 RSSA_HUMAN (1-295): 2.16e-153: 432: 100.00		WWP1_HUMAN (2-395): 4.38e-20: 97.5: 15.47