Protein: DUS1
Dual specificity protein phosphatase 1 (EC 3.1.3.16) (EC 3.1.3.48) (Dual specificity protein phosphatase hVH1) (Mitogen-activated protein kinase phosphatase 1) (MAP kinase phosphatase 1) (MKP-1) (Protein-tyrosine phosphatase CL100)

Gene: DUS1, DUSP1
Organism: Homo sapiens
Interactions: 103
UniProt ID: P28562

Gene Ontology (top 5):
GO:0001706 - endoderm formation
GO:0004722 - protein serine/threonine phosphatase activity
GO:0004725 - protein tyrosine phosphatase activity
GO:0005634 - nucleus
GO:0005737 - cytoplasm

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

659288

MK14
Mitogen-activated protein kinase 14

7

20

Small-scale

0.967

High

658798

MK01
Mitogen-activated protein kinase 1

6

20

Small-scale

0.949

High

647475

MK03
Mitogen-activated protein kinase 3

4

20

Small-scale

0.902

High

659258

MK08
Mitogen-activated protein kinase 8

2

20

Small-scale

0.800

High

659259

MK09
Mitogen-activated protein kinase 9

2

20

Small-scale

0.776

High

659252

DUS1
Dual specificity protein phosphatase 1

2

15

High-throughput

0.754

High

659264

MK10
Mitogen-activated protein kinase 10

1

20

Small-scale

0.665

High

659277

SKP2
S-phase kinase-associated protein 2

3

3

Small-scale

0.646

High

659276

ILF3
Interleukin enhancer-binding factor 3

3

2

Small-scale

0.643

High

659284

ELAV1
ELAV-like protein 1

3

3

Small-scale

0.643

High

158403

IKKB
Inhibitor of nuclear factor kappa-B kinase subunit beta

1

4

Small-scale

0.618

High

167478

IKKA
Inhibitor of nuclear factor kappa-B kinase subunit alpha

1

6

Small-scale

0.618

High

659256

KPCI
Protein kinase C iota type

1

1

Small-scale

0.618

High

659261

DUS3
Dual specificity protein phosphatase 3

1

15

High-throughput

0.618

High

659285

MK11
Mitogen-activated protein kinase 11

1

20

Small-scale

0.618

High

128035

IF2B3
Insulin-like growth factor 2 mRNA-binding protein 3

2

9

High-throughput

0.571

High

235721

HNRPQ
Heterogeneous nuclear ribonucleoprotein Q

2

4

High-throughput

0.571

High

322220

STAU1
Double-stranded RNA-binding protein Staufen homolog 1

2

1

High-throughput

0.571

High

388247

HSPB1
Heat shock protein beta-1

2

6

High-throughput

0.571

High

516370

PABP1
Polyadenylate-binding protein 1

2

3

High-throughput

0.571

High

540905

HNRPL
Heterogeneous nuclear ribonucleoprotein L

2

10

High-throughput

0.571

High

659275

ILF2
Interleukin enhancer-binding factor 2

2

1

High-throughput

0.571

High

659278

PABP4
Polyadenylate-binding protein 4

2

3

High-throughput

0.571

High

551612

DESP
Desmoplakin

2

7

High-throughput

0.571

High

641626

U2AF2
Splicing factor U2AF 65 kDa subunit

2

7

High-throughput

0.571

High

643428

PTBP1
Polypyrimidine tract-binding protein 1

2

9

High-throughput

0.571

High

659257

LPPRC
Leucine-rich PPR motif-containing protein, mitochondrial

2

7

High-throughput

0.571

High

659268

HNRPK
Heterogeneous nuclear ribonucleoprotein K

2

9

High-throughput

0.571

High

659273

KHDR1
KH domain-containing, RNA-binding, signal transduction-associated protein 1

2

3

High-throughput

0.571

High

659281

CAPR1
Caprin-1

2

2

High-throughput

0.571

High

659283

PCBP2
Poly(rC)-binding protein 2

2

5

High-throughput

0.571

High

659298

PABP2
Polyadenylate-binding protein 2

2

4

High-throughput

0.571

High

659300

RB6I2
ELKS/Rab6-interacting/CAST family member 1

2

8

High-throughput

0.571

High

659301

SRRM1
Serine/arginine repetitive matrix protein 1

2

4

High-throughput

0.571

High

659302

CCAR2
Cell cycle and apoptosis regulator protein 2

2

2

High-throughput

0.571

High

659306

HNRLL
Heterogeneous nuclear ribonucleoprotein L-like

2

9

High-throughput

0.571

High

659315

ROAA
Heterogeneous nuclear ribonucleoprotein A/B

2

6

High-throughput

0.571

High

659317

SLIRP
SRA stem-loop-interacting RNA-binding protein, mitochondrial

2

6

High-throughput

0.571

High

659318

PABP3
Polyadenylate-binding protein 3

2

3

High-throughput

0.571

High

659326

IF2B2
Insulin-like growth factor 2 mRNA-binding protein 2

2

10

High-throughput

0.571

High

659265

PRPS1
Ribose-phosphate pyrophosphokinase 1

2

0

High-throughput

0.547

High

659269

YBOX1
Y-box-binding protein 1

2

0

High-throughput

0.547

High

659274

NCBP1
Nuclear cap-binding protein subunit 1

2

0

High-throughput

0.547

High

659291

LARP1
La-related protein 1

2

0

High-throughput

0.547

High

659295

DHX30
ATP-dependent RNA helicase DHX30

2

0

High-throughput

0.547

High

659299

LYRIC
Protein LYRIC

2

0

High-throughput

0.547

High

659270

RT35
Small ribosomal subunit protein mS35

2

2

High-throughput

0.521

High

659271

TIAR
Nucleolysin TIAR

1

4

Small-scale

0.515

High

659325

AMFR
E3 ubiquitin-protein ligase AMFR

1

1

Small-scale

0.512

High

659286

HSPB2
Heat shock protein beta-2

1

6

High-throughput

0.508

High

474934

UBB
Polyubiquitin-B [Cleaved into: Ubiquitin]

1

3

Small-scale

0.501

High

659272

ROR2
Tyrosine-protein kinase transmembrane receptor ROR2

1

20

High-throughput

0.494

High

659292

LMTK1
Serine/threonine-protein kinase LMTK1

1

20

High-throughput

0.494

High

659324

RPA12
DNA-directed RNA polymerase I subunit RPA12

1

1

High-throughput

0.494

High

496372

TAU
Microtubule-associated protein tau

1

0

Small-scale

0.480

High

118539

EYA2
Eyes absent homolog 2

1

1

High-throughput

0.479

High

377114

GCR
Glucocorticoid receptor

1

3

Small-scale

0.479

High

430449

APT
Adenine phosphoribosyltransferase

1

2

High-throughput

0.479

High

573581

PTN1
Tyrosine-protein phosphatase non-receptor type 1

1

6

High-throughput

0.479

High

623717

PPAC
Low molecular weight phosphotyrosine protein phosphatase

1

1

High-throughput

0.479

High

637331

PSA1
Proteasome subunit alpha type-1

1

1

High-throughput

0.479

High

659254

TIA1
Cytotoxic granule associated RNA binding protein TIA1

1

4

Small-scale

0.479

High

659255

HSP74
Heat shock 70 kDa protein 4

1

9

Small-scale

0.479

High

659287

NF2L2
Nuclear factor erythroid 2-related factor 2

1

1

Small-scale

0.479

High

659293

UBR3
E3 ubiquitin-protein ligase UBR3

1

1

Small-scale

0.479

High

659294

UBP49
Ubiquitin carboxyl-terminal hydrolase 49

1

3

Small-scale

0.479

High

659296

HDDC2
5'-deoxynucleotidase HDDC2

1

2

High-throughput

0.479

High

659305

UBP33
Ubiquitin carboxyl-terminal hydrolase 33

1

7

Small-scale

0.479

High

659312

ABHEB
Putative protein-lysine deacylase ABHD14B

1

2

High-throughput

0.479

High

659313

PSMD1
26S proteasome non-ATPase regulatory subunit 1

1

2

High-throughput

0.479

High

659314

PARK7
Parkinson disease protein 7

1

5

High-throughput

0.479

High

659316

MTMRC
Myotubularin-related protein 12

1

2

High-throughput

0.479

High

569239

CEBPB
CCAAT/enhancer-binding protein beta

1

0

Small-scale

0.458

High

659304

PAF1
RNA polymerase II-associated factor 1 homolog

1

0

Small-scale

0.458

High

659310

FBX32
F-box only protein 32

1

0

Small-scale

0.458

High

659323

NDUAD
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 13

1

0

High-throughput

0.458

High

659280

CUL1
Cullin-1

1

2

Small-scale

0.445

High

525426

COX41
Cytochrome c oxidase subunit 4 isoform 1, mitochondrial

1

3

High-throughput

0.437

High

585951

SPEE
Spermidine synthase

1

5

High-throughput

0.437

High

659253

METK2
S-adenosylmethionine synthase isoform type-2

1

1

High-throughput

0.437

High

659263

BIEA
Biliverdin reductase A

1

1

High-throughput

0.437

High

659267

COPZ1
Coatomer subunit zeta-1

1

7

High-throughput

0.437

High

659289

SGMR2
Sigma intracellular receptor 2

1

2

High-throughput

0.437

High

659297

TRI46
Tripartite motif-containing protein 46

1

5

Small-scale

0.437

High

659308

AP3S1
AP-3 complex subunit sigma-1

1

7

High-throughput

0.437

High

659320

ECHD1
Ethylmalonyl-CoA decarboxylase

1

1

High-throughput

0.437

High

254670

PTCD1
Pentatricopeptide repeat-containing protein 1, mitochondrial

2

0

High-throughput

0.298

High

327364

TRUB2
Pseudouridylate synthase TRUB2, mitochondrial

2

0

High-throughput

0.298

High

659260

RT29
Small ribosomal subunit protein mS29

2

0

High-throughput

0.298

High

659262

SSRD
Translocon-associated protein subunit delta

2

0

High-throughput

0.298

High

659266

CKS1
Cyclin-dependent kinases regulatory subunit 1

2

0

Small-scale

0.298

High

659279

RM49
Large ribosomal subunit protein mL49

2

0

High-throughput

0.298

High

659290

RUSD3
Mitochondrial mRNA pseudouridine synthase RPUSD3

2

0

High-throughput

0.298

High

659303

RM50
Large ribosomal subunit protein mL50

2

0

High-throughput

0.298

High

659309

RT31
Small ribosomal subunit protein mS31

2

0

High-throughput

0.298

High

659319

RM17
Large ribosomal subunit protein bL17m

2

0

High-throughput

0.298

High

659321

DDX28
Probable ATP-dependent RNA helicase DDX28

2

0

High-throughput

0.298

High

659322

FAKD2
FAST kinase domain-containing protein 2, mitochondrial

2

0

High-throughput

0.298

High

659311

STALP
AMSH-like protease

1

0

Small-scale

0.292

High

239251

ICMT
Protein-S-isoprenylcysteine O-methyltransferase

1

0

High-throughput

0.249

Low

659282

SNX17
Sorting nexin-17

1

0

High-throughput

0.249

Low

659307

RTF1
RNA polymerase-associated protein RTF1 homolog

1

0

Small-scale

0.249

Low


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Last updated: 15 Jul 2024