Interactor 1: IF4E (P06730)
Eukaryotic translation initiation factor 4E (eIF-4E) (eIF4E) (eIF-4F 25 kDa subunit) (mRNA cap-binding protein)
Gene: EIF4E
Interactor 2: 4EBP2 (Q13542)
Eukaryotic translation initiation factor 4E-binding protein 2 (4E-BP2) (eIF4E-binding protein 2)
Gene: EIF4EBP2
Species: Homo sapiens
Source: mint
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.97 | 1.00 | 0.989 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 32296183, 7935836, 25416956, 26186194, 20347422, 28514442, 7651417, 24981860, 33961781, 24722188, 24207126, 16189514, 15153109, 16271312, 17316564, 31515488, unassigned1304, unassigned3799 |
| Identification Methods | two hybrid, far western blotting, affinity chromatography technology, pull down, nuclear magnetic resonance, isothermal titration calorimetry, two hybrid pooling approach, classical fluorescence spectroscopy, surface plasmon resonance, validated two hybrid and 5 others
more... |
| Interaction Type | direct interaction, physical association, association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | IF4E~eIF_4EBP |
| Common GO terms | GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0098794 - postsynapse |
| Homologous interactions | 15 |
Homologous interactions
Color coding for hit scores 
|
|
|||||||||||||
| + | Mm |   |
 |
|||||||||||
| + | Rn | |
|
|||||||||||
| + | Hs | |
|
|||||||||||
| + | Mm | |
|
|||||||||||
| + | Hs | |
|
|||||||||||
| + | Dm | |
|
|||||||||||
| + | Hs | |
|
|||||||||||
| + | Dm | |
|
|||||||||||
| + | Hs | |
|
|||||||||||
| + | Dm | |
|
|||||||||||
| + | Hs | |
|
|||||||||||
| + | Dm | |
|
|||||||||||
| + | Mm | |
|
|||||||||||
| + | Dm | |
|
|||||||||||
| + | Hs | |
|
|||||||||||
Service provided by Combinatics, Japan
Last updated: 11Aug2025
