HitPredict

Interactor 1: ENOA (P06733)
Alpha-enolase (EC 4.2.1.11) (2-phospho-D-glycerate hydro-lyase) (C-myc promoter-binding protein) (Enolase 1) (MBP-1) (MPB-1) (Non-neural enolase) (NNE) (Phosphopyruvate hydratase) (Plasminogen-binding protein)
Gene: ENO1

Interactor 2: ENOA (P06733)
Alpha-enolase (EC 4.2.1.11) (2-phospho-D-glycerate hydro-lyase) (C-myc promoter-binding protein) (Enolase 1) (MBP-1) (MPB-1) (Non-neural enolase) (NNE) (Phosphopyruvate hydratase) (Plasminogen-binding protein)
Gene: ENO1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.56 1.00 0.754

The method score is based on:

Property Details
Experiments 25253489, 31839598
Identification Methods cross-linking study
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains Enolase_C~Enolase_C, Enolase_C~Enolase_N, Enolase_N~Enolase_N
Common GO terms GO:0000015 - phosphopyruvate hydratase complex
GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0000287 - magnesium ion binding
GO:0000977 - RNA polymerase II transcription regulatory region sequence-specific DNA binding
GO:0001222 - transcription corepressor binding
and 28 others

more...
Homologous interactions 13

Homologous interactions

Color coding for hit scores

1 434
Hs

1 434
+ Hs
+ Hs
+ Mm
+ Hs
+ Hs
+ Dm
+ Sc
+ Sc
+ Sc
+ Sc
+ Sa
+ Sp
+ Ec

Service provided by Combinatics, Japan

Last updated: 11Aug2025