HitPredict

Interactor 1: MLC1 (P06742)
Myosin light chain alkali
Gene: MLC1

Interactor 2: TNNC1 (P47947)
Troponin C, isoform 1
Gene: TpnC41C

Species: Drosophila melanogaster

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.54	1.00	0.737

Property	Details
Experiments	22036573, 38944040
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	EF-hand_7~EF-hand_7
Common GO terms	GO:0005509 - calcium ion binding
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 155 Dm			1 154
+	Dm
		446293 MLC1_DROME (1-155): 2.97e-63: 192: 100.00		Q7K860_DROME (4-151): 1.2e-46: 150: 59.73
+	Dm
		446334 MLC1_DROME (1-155): 2.97e-63: 192: 100.00		Q9VMT2_DROME (8-151): 6.57e-40: 133: 56.25
+	Hs
		437557 MYL1_HUMAN (3-149): 1.75e-63: 194: 39.07		CALM1_HUMAN (6-76): 9.82e-14: 66: 33.80
+	Hs
		437558 MYL1_HUMAN (3-149): 1.75e-63: 194: 39.07		CALM3_HUMAN (6-76): 9.82e-14: 66: 33.80
+	Hs
		516323 MYL6_HUMAN (1-150): 1.2e-52: 165: 37.66		CALM1_HUMAN (6-76): 9.82e-14: 66: 33.80
+	Hs
		516397 MYL6_HUMAN (1-150): 1.2e-52: 165: 37.66		CALM2_HUMAN (6-76): 9.82e-14: 66: 33.80
+	Hs
		516488 MYL6_HUMAN (1-150): 1.2e-52: 165: 37.66		CALM3_HUMAN (6-76): 9.82e-14: 66: 33.80
+	Hs
		516458 CALM3_HUMAN (2-149): 1.13e-47: 153: 27.33		CALM3_HUMAN (6-76): 9.82e-14: 66: 33.80
+	Hs
		516311 CALM1_HUMAN (2-149): 1.13e-47: 153: 27.33		CALL3_HUMAN (77-151): 1.2e-12: 63.3: 44.00
+	Hs
		516385 CALM2_HUMAN (2-149): 1.13e-47: 153: 27.33		CALL3_HUMAN (77-151): 1.2e-12: 63.3: 44.00
+	Hs
		516305 MYL6B_HUMAN (3-149): 1.9e-45: 149: 35.10		CALM1_HUMAN (6-76): 9.82e-14: 66: 33.80
+	Hs
		516379 MYL6B_HUMAN (3-149): 1.9e-45: 149: 35.10		CALM2_HUMAN (6-76): 9.82e-14: 66: 33.80
+	Hs
		516461 MYL6B_HUMAN (3-149): 1.9e-45: 149: 35.10		CALM3_HUMAN (6-76): 9.82e-14: 66: 33.80
+	At
		947493 CALM7_ARATH (2-149): 2.03e-45: 147: 28.00		CALM6_ARATH (6-76): 3.21e-13: 64.8: 33.80
+	Zm
		25216 A0A1D6INZ6_MAIZE (1-76): 2.57e-15: 73.3: 17.95		A0A1D6INZ6_MAIZE (40-149): 1.75e-25: 101: 46.36
+	At
		1057375 CDPK1_ARATH (39-149): 4.31e-11: 61.8: 16.22		CDPK1_ARATH (66-148): 2.98e-13: 67.9: 30.12
+	Gm
		1284629 Q84P28_SOYBN (69-149): 1.73e-10: 59.8: 19.75		Q84P28_SOYBN (71-148): 3.11e-12: 64.8: 29.49