HitPredict

Interactor 1: NPM (P06748)
Nucleophosmin (NPM) (Nucleolar phosphoprotein B23) (Nucleolar protein NO38) (Numatrin)
Gene: NPM1

Interactor 2: GEMI5 (Q8TEQ6)
Gem-associated protein 5 (Gemin5)
Gene: GEMIN5

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	35271311
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003723 - RNA binding GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005737 - cytoplasm GO:0005829 - cytosol and 1 others more... GO:0016020 - membrane
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 294 Hs			1 1508
+	Hs
		447501 NPM_HUMAN (1-294): 1.76e-143: 406: 100.00		NLE1_HUMAN (519-874): 7.27e-59: 213: 13.94
+	Hs
		446952 NPM_HUMAN (1-294): 1.76e-143: 406: 100.00		TBL3_HUMAN (1-254): 4.9e-44: 175: 17.02
+	Hs
		447586 NPM_HUMAN (1-294): 1.76e-143: 406: 100.00		WDR3_HUMAN (491-937): 1.75e-33: 142: 11.77
+	Hs
		447576 NPM_HUMAN (1-294): 1.76e-143: 406: 100.00		FZR1_HUMAN (236-500): 7.64e-13: 74.8: 20.90
+	Hs
		288793 NPM3_HUMAN (10-119): 6.16e-58: 185: 43.75		NLE1_HUMAN (519-874): 7.27e-59: 213: 13.94
+	Hs
		288642 NPM3_HUMAN (10-119): 6.16e-58: 185: 43.75		TBL3_HUMAN (1-254): 4.9e-44: 175: 17.02
+	Hs
		288819 NPM3_HUMAN (10-119): 6.16e-58: 185: 43.75		WDR3_HUMAN (491-937): 1.75e-33: 142: 11.77
+	Hs
		288814 NPM3_HUMAN (10-119): 6.16e-58: 185: 43.75		FZR1_HUMAN (236-500): 7.64e-13: 74.8: 20.90