HitPredict

Interactor 1: HMGB1 (P09429)
High mobility group protein B1 (High mobility group protein 1) (HMG-1)
Gene: HMGB1

Interactor 2: VIGLN (Q00341)
Vigilin (High density lipoprotein-binding protein) (HDL-binding protein)
Gene: HDLBP

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.43	0.60	0.508

Property	Details
Experiments	31694235
Identification Methods	two hybrid
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003723 - RNA binding GO:0005634 - nucleus
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 215 Hs			1 1268
+	Hs
		643325 HMGB2_HUMAN (1-187): 7e-43: 145: 82.89		VIGLN_HUMAN (1-1268): 0: 939: 100.00
+	Hs
		959373 SSRP1_HUMAN (53-164): 1.59e-28: 114: 37.50		VIGLN_HUMAN (1-1268): 0: 939: 100.00
+	Hs
		297485 TOX4_HUMAN (91-163): 1.19e-27: 111: 38.36		VIGLN_HUMAN (1-1268): 0: 939: 100.00
+	Hs
		818352 SOX2_HUMAN (3-94): 2.8e-25: 102: 23.91		FUBP3_HUMAN (796-1122): 1.09e-33: 140: 16.85
+	Hs
		128153 SSRP1_HUMAN (53-164): 1.59e-28: 114: 37.50		IF2B3_HUMAN (23-228): 7.78e-25: 113: 15.70
+	Hs
		996938 SSRP1_HUMAN (53-164): 1.59e-28: 114: 37.50		IF2B1_HUMAN (58-368): 1.59e-20: 99.6: 15.52
+	Hs
		643348 HMGB2_HUMAN (1-187): 7e-43: 145: 82.89		PCBP1_HUMAN (1128-1232): 3.39e-10: 65.3: 16.19
+	Hs
		818543 SOX2_HUMAN (3-94): 2.8e-25: 102: 23.91		IF2B1_HUMAN (58-368): 1.59e-20: 99.6: 15.52
+	Hs
		818673 SOX2_HUMAN (3-94): 2.8e-25: 102: 23.91		IF2B2_HUMAN (920-1124): 2.37e-18: 92.7: 14.76
+	Hs
		1072162 CIC_HUMAN (3-96): 2.76e-12: 67: 22.34		PCBP2_HUMAN (968-1137): 1.24e-22: 103: 20.57
+	Hs
		1071975 CIC_HUMAN (3-96): 2.76e-12: 67: 22.34		PCBP1_HUMAN (1128-1232): 3.39e-10: 65.3: 16.19