Interactor 1: TPM1 (P09493)
Tropomyosin alpha-1 chain (Alpha-tropomyosin) (Tropomyosin-1)
Gene: TPM1

Interactor 2: TPM1 (P09493)
Tropomyosin alpha-1 chain (Alpha-tropomyosin) (Tropomyosin-1)
Gene: TPM1

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.58 1.00 0.768

The method score is based on:

Property Details
Experiments 7568216, 3857586
Identification Methods affinity chromatography technology, pull down
Interaction Type physical association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains Tropomyosin~Tropomyosin
Common GO terms GO:0001725 - stress fiber
GO:0003065 - positive regulation of heart rate by epinephrine
GO:0003779 - actin binding
GO:0005200 - structural constituent of cytoskeleton
GO:0005829 - cytosol
and 30 others

more...

Homologous interactions 15

Homologous interactions

Color coding for hit scores

1 284
Hs

1 284
+ Dm
+ Hs
+ Gg
+ Rn
+ Gg
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Mm

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024