Interactor 1: TPM1 (P09493)
Tropomyosin alpha-1 chain (Alpha-tropomyosin) (Tropomyosin-1)
Gene: TPM1

Interactor 2: TPM4 (P67936)
Tropomyosin alpha-4 chain (TM30p1) (Tropomyosin-4)
Gene: TPM4

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.85 1.00 0.923

The method score is based on:

Property Details
Experiments 33961781, 25416956, 26186194, 28514442, 35235311
Identification Methods affinity chromatography technology, two hybrid, cross-linking study, anti tag coimmunoprecipitation
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains Tropomyosin~Tropomyosin
Common GO terms GO:0001725 - stress fiber
GO:0005829 - cytosol
GO:0005856 - cytoskeleton
GO:0005862 - muscle thin filament tropomyosin
GO:0005884 - actin filament
and 5 others

more...

Homologous interactions 15

Homologous interactions

Color coding for hit scores

1 284
Hs

1 248
+ Gg
+ Rn
+ Hs
+ Gg
+ Hs
+ Hs
+ Hs
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+ Hs
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+ Dm
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024