HitPredict

Interactor 1: NFM (P07197)
Neurofilament medium polypeptide (NF-M) (160 kDa neurofilament protein) (Neurofilament 3) (Neurofilament triplet M protein)
Gene: NEFM

Interactor 2: CAN1 (P07384)
Calpain-1 catalytic subunit (EC 3.4.22.52) (Calcium-activated neutral proteinase 1) (CANP 1) (Calpain mu-type) (Calpain-1 large subunit) (Cell proliferation-inducing gene 30 protein) (Micromolar-calpain) (muCANP)
Gene: CAPN1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	0.50	0.574

Property	Details
Experiments	28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 916 Hs			1 714
+	Hs
		457098 AINX_HUMAN (8-494): 2.99e-91: 300: 47.69		CAN1_HUMAN (1-714): 0: 941: 100.00
+	Hs
		457028 VIME_HUMAN (8-413): 1.86e-77: 261: 44.61		CAN1_HUMAN (1-714): 0: 941: 100.00
+	Hs
		457038 DESM_HUMAN (93-413): 5.52e-63: 222: 45.79		CAN1_HUMAN (1-714): 0: 941: 100.00
+	Hs
		1157225 AINX_HUMAN (8-494): 2.99e-91: 300: 47.69		CAN12_HUMAN (23-714): 0: 726: 41.56
+	Hs
		474427 VIME_HUMAN (8-413): 1.86e-77: 261: 44.61		CALM3_HUMAN (474-617): 2.38e-15: 75.4: 15.86
+	Hs
		451315 NFM_HUMAN (1-916): 8.69e-65: 237: 100.00		CALM3_HUMAN (474-617): 2.38e-15: 75.4: 15.86
+	Hs
		704428 MYH9_HUMAN (426-916): 9.84e-20: 97.6: 9.37		GRAN_HUMAN (528-712): 2.48e-62: 209: 29.19