HitPredict

Interactor 1: CSF1R (P09581)
Macrophage colony-stimulating factor 1 receptor (CSF-1 receptor) (CSF-1-R) (CSF-1R) (M-CSF-R) (EC 2.7.10.1) (Proto-oncogene c-Fms) (CD antigen CD115)
Gene: CSF1R

Interactor 2: P85A (P26450)
Phosphatidylinositol 3-kinase regulatory subunit alpha (PI3-kinase regulatory subunit alpha) (PI3K regulatory subunit alpha) (PtdIns-3-kinase regulatory subunit alpha) (Phosphatidylinositol 3-kinase 85 kDa regulatory subunit alpha) (PI3-kinase subunit p85-alpha) (PtdIns-3-kinase regulatory subunit p85-alpha)
Gene: Pik3r1

Species: Mus musculus

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.72 1.00 0.854

The method score is based on:

Property Details
Experiments 8947469, 9312046, 17420256
Identification Methods affinity chromatography technology, two hybrid
Interaction Type physical association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains PK_Tyr_Ser-Thr~SH2
Common GO terms GO:0010628 - positive regulation of gene expression
GO:0016020 - membrane
GO:0019903 - protein phosphatase binding
GO:0030316 - osteoclast differentiation
GO:0030335 - positive regulation of cell migration
and 2 others

more...
Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 977
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024