Interactor 1: EZH2 (Q61188)
Histone-lysine N-methyltransferase EZH2 (EC 2.1.1.356) (ENX-1) (Enhancer of zeste homolog 2)
Gene: EZH2

Interactor 2: RBL2 (Q64700)
Retinoblastoma-like protein 2 (130 kDa retinoblastoma-associated protein) (p130) (Retinoblastoma-related protein 2) (RBR-2) (pRb2)
Gene: RBL2

Species: Mus musculus

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.38 0.60 0.479

The method score is based on:

Property Details
Experiments 15077161
Identification Methods affinity chromatography technology
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0006357 - regulation of transcription by RNA polymerase II
GO:0010629 - negative regulation of gene expression
GO:1990841 - promoter-specific chromatin binding
and 1 others

more...

Homologous interactions 9

Homologous interactions

Color coding for hit scores

1 746
Mm

1 1135
+ Hs
+ Rn
+ Hs
+ Hs
+ Hs
+ Hs
+ Dm
+ Dm
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024