HitPredict

Interactor 1: ROA1 (P09651)
Heterogeneous nuclear ribonucleoprotein A1 (hnRNP A1) (Helix-destabilizing protein) (Single-strand RNA-binding protein) (hnRNP core protein A1) [Cleaved into: Heterogeneous nuclear ribonucleoprotein A1, N-terminally processed]
Gene: HNRNPA1

Interactor 2: 1433T (P27348)
14-3-3 protein theta (14-3-3 protein T-cell) (14-3-3 protein tau) (Protein HS1)
Gene: YWHAQ

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.58	0.60	0.595

Property	Details
Experiments	25324306, 15161933
Identification Methods	affinity chromatography technology, pull down
Interaction Type	physical association, direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0016020 - membrane GO:0019904 - protein domain specific binding GO:0070062 - extracellular exosome
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 372 Hs			1 245
+	Hs
		453256 ROA1_HUMAN (1-372): 3.69e-61: 202: 100.00		1433E_HUMAN (2-243): 1.31e-144: 406: 63.53
+	Hs
		453268 ROA1_HUMAN (1-372): 3.69e-61: 202: 100.00		1433Z_HUMAN (1-245): 1.75e-141: 397: 79.59
+	Hs
		609795 ROA2_HUMAN (1-339): 4.42e-56: 188: 59.00		1433E_HUMAN (2-243): 1.31e-144: 406: 63.53
+	Hs
		453175 ROA1_HUMAN (1-372): 3.69e-61: 202: 100.00		1433B_HUMAN (1-242): 5.01e-139: 391: 81.82
+	Hs
		852009 ROA3_HUMAN (7-202): 5.98e-55: 186: 85.71		1433E_HUMAN (2-243): 1.31e-144: 406: 63.53
+	Hs
		609720 ROA2_HUMAN (1-339): 4.42e-56: 188: 59.00		1433T_HUMAN (1-245): 9.47e-142: 398: 100.00
+	Hs
		609804 ROA2_HUMAN (1-339): 4.42e-56: 188: 59.00		1433Z_HUMAN (1-245): 1.75e-141: 397: 79.59
+	Mm
		935646 ROA0_MOUSE (9-186): 4.93e-59: 195: 59.55		1433F_MOUSE (2-242): 4.62e-106: 308: 71.43
+	Hs
		609792 ROA2_HUMAN (1-339): 4.42e-56: 188: 59.00		1433G_HUMAN (1-242): 5.48e-105: 305: 70.33
+	Mm
		935716 HNRDL_MOUSE (2-283): 2.78e-55: 185: 32.41		1433F_MOUSE (2-242): 4.62e-106: 308: 71.43
+	Mm
		910326 ROAA_MOUSE (2-100): 6.42e-18: 84.8: 29.29		1433E_MOUSE (2-243): 1.31e-144: 406: 63.53
+	Hs
		909516 PABP4_HUMAN (102-190): 3.52e-15: 79: 15.56		1433E_HUMAN (2-243): 1.31e-144: 406: 63.53
+	Hs
		927029 HNRPD_HUMAN (2-101): 4.8e-18: 86.4: 31.00		1433Z_HUMAN (1-245): 1.75e-141: 397: 79.59
+	Hs
		646864 PABP4_HUMAN (102-190): 3.52e-15: 79: 15.56		1433T_HUMAN (1-245): 9.47e-142: 398: 100.00
+	Hs
		927003 PABP4_HUMAN (102-190): 3.52e-15: 79: 15.56		1433Z_HUMAN (1-245): 1.75e-141: 397: 79.59
+	Hs
		683319 PABP4_HUMAN (102-190): 3.52e-15: 79: 15.56		1433B_HUMAN (1-242): 5.01e-139: 391: 81.82
+	Hs
		684027 HNRPD_HUMAN (2-101): 4.8e-18: 86.4: 31.00		1433S_HUMAN (1-236): 9.86e-108: 312: 71.85
+	Hs
		981998 HNRPD_HUMAN (2-101): 4.8e-18: 86.4: 31.00		1433F_HUMAN (2-242): 7.16e-106: 307: 71.43