HitPredict

Interactor 1: ROA1 (P09651)
Heterogeneous nuclear ribonucleoprotein A1 (hnRNP A1) (Helix-destabilizing protein) (Single-strand RNA-binding protein) (hnRNP core protein A1) [Cleaved into: Heterogeneous nuclear ribonucleoprotein A1, N-terminally processed]
Gene: HNRNPA1

Interactor 2: FBW1B (Q9UKB1)
F-box/WD repeat-containing protein 11 (F-box and WD repeats protein beta-TrCP2) (F-box/WD repeat-containing protein 1B) (Homologous to Slimb protein) (HOS)
Gene: FBXW11

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	25900982
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 372 Hs			1 542
+	Hs
		162182 HNRDL_HUMAN (2-283): 5.5e-56: 190: 32.41		FBW1B_HUMAN (1-542): 9.69e-174: 503: 100.00
+	Hs
		610101 ROA2_HUMAN (1-339): 4.42e-56: 188: 59.00		FBW1B_HUMAN (1-542): 9.69e-174: 503: 100.00
+	Hs
		852199 ROA3_HUMAN (7-202): 5.98e-55: 186: 85.71		FBW1B_HUMAN (1-542): 9.69e-174: 503: 100.00
+	Hs
		453715 ROA1_HUMAN (1-372): 3.69e-61: 202: 100.00		FBW1A_HUMAN (26-542): 3.86e-155: 458: 84.59
+	Hs
		162186 HNRDL_HUMAN (2-283): 5.5e-56: 190: 32.41		FBW1A_HUMAN (26-542): 3.86e-155: 458: 84.59
+	Hs
		610117 ROA2_HUMAN (1-339): 4.42e-56: 188: 59.00		FBW1A_HUMAN (26-542): 3.86e-155: 458: 84.59
+	Hs
		852208 ROA3_HUMAN (7-202): 5.98e-55: 186: 85.71		FBW1A_HUMAN (26-542): 3.86e-155: 458: 84.59
+	Hs
		1306041 ROAA_HUMAN (6-184): 1.25e-35: 134: 39.44		FBW1B_HUMAN (1-542): 9.69e-174: 503: 100.00
+	Hs
		1306046 ROAA_HUMAN (6-184): 1.25e-35: 134: 39.44		FBW1A_HUMAN (26-542): 3.86e-155: 458: 84.59
+	Hs
		453519 ROA1_HUMAN (1-372): 3.69e-61: 202: 100.00		FBXW7_HUMAN (18-424): 1.12e-72: 246: 20.29
+	Hs
		609988 ROA2_HUMAN (1-339): 4.42e-56: 188: 59.00		FBXW7_HUMAN (18-424): 1.12e-72: 246: 20.29
+	Hs
		852125 ROA3_HUMAN (7-202): 5.98e-55: 186: 85.71		FBXW7_HUMAN (18-424): 1.12e-72: 246: 20.29
+	Hs
		196946 ROA1_HUMAN (1-372): 3.69e-61: 202: 100.00		PRP4_HUMAN (320-536): 4.83e-42: 159: 22.13
+	Hs
		1048172 HNRPD_HUMAN (2-101): 4.8e-18: 86.4: 31.00		FBXW7_HUMAN (18-424): 1.12e-72: 246: 20.29
+	Hs
		453251 ROA1_HUMAN (1-372): 3.69e-61: 202: 100.00		WDR5_HUMAN (80-265): 5.44e-16: 81.1: 11.92
+	Hs
		162000 HNRDL_HUMAN (2-283): 5.5e-56: 190: 32.41		WDR5_HUMAN (80-265): 5.44e-16: 81.1: 11.92
+	Hs
		609790 ROA2_HUMAN (1-339): 4.42e-56: 188: 59.00		WDR5_HUMAN (80-265): 5.44e-16: 81.1: 11.92
+	Hs
		852006 ROA3_HUMAN (7-202): 5.98e-55: 186: 85.71		WDR5_HUMAN (80-265): 5.44e-16: 81.1: 11.92
+	Hs
		903463 ROAA_HUMAN (6-184): 1.25e-35: 134: 39.44		WDR5_HUMAN (80-265): 5.44e-16: 81.1: 11.92
+	Hs
		903216 HNRPD_HUMAN (2-101): 4.8e-18: 86.4: 31.00		WDR5_HUMAN (80-265): 5.44e-16: 81.1: 11.92