HitPredict

Interactor 1: AST8 (P09775)
Achaete-scute complex protein T8 (Protein asense)
Gene: ase

Interactor 2: EMC (P18491)
Protein extra-macrochaetae
Gene: EMC

Species: Drosophila melanogaster

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.34	1.00	0.590

Property	Details
Experiments	9371806
Identification Methods	two hybrid
Interaction Type	physical association

Property	Details
Interacting Pfam domains	HLH~HLH
Common GO terms	GO:0005634 - nucleus GO:0008407 - chaeta morphogenesis GO:0046982 - protein heterodimerization activity
Homologous interactions	13

Homologous interactions

Color coding for hit scores

	1 486 Dm			1 199
+	Dm
		485922 AST4_DROME (105-241): 7.1e-28: 115: 37.96		EMC_DROME (1-199): 3.43e-112: 320: 100.00
+	Dm
		485888 AST5_DROME (151-231): 1.56e-23: 99: 54.22		EMC_DROME (1-199): 3.43e-112: 320: 100.00
+	Dm
		454857 AST3_DROME (136-273): 1.18e-15: 78.7: 35.90		EMC_DROME (1-199): 3.43e-112: 320: 100.00
+	Hs
		814914 ASCL3_HUMAN (83-254): 3.3e-32: 123: 26.74		ID4_HUMAN (38-103): 2.02e-31: 113: 41.25
+	Hs
		814916 NGN3_HUMAN (71-270): 5.79e-30: 118: 16.43		ID4_HUMAN (38-103): 2.02e-31: 113: 41.25
+	Hs
		780989 ASCL3_HUMAN (83-254): 3.3e-32: 123: 26.74		ID1_HUMAN (38-99): 7.16e-29: 106: 47.76
+	Hs
		524549 LYL1_HUMAN (125-254): 1.08e-23: 102: 28.36		ID4_HUMAN (38-103): 2.02e-31: 113: 41.25
+	Hs
		524547 LYL1_HUMAN (125-254): 1.08e-23: 102: 28.36		ID1_HUMAN (38-99): 7.16e-29: 106: 47.76
+	Hs
		780971 ASCL4_HUMAN (101-243): 1.56e-22: 96.1: 25.18		ID1_HUMAN (38-99): 7.16e-29: 106: 47.76
+	Hs
		568188 TAL1_HUMAN (130-240): 6.47e-17: 83.8: 29.83		ID4_HUMAN (38-103): 2.02e-31: 113: 41.25
+	Hs
		970583 ASCL4_HUMAN (101-243): 1.56e-22: 96.1: 25.18		ID2_HUMAN (38-103): 8.94e-25: 95.6: 41.67
+	Mm
		589139 TAL1_MOUSE (130-239): 1.09e-16: 83: 30.09		ID1_MOUSE (38-99): 5.12e-29: 107: 47.76
+	Hs
		524557 LYL1_HUMAN (125-254): 1.08e-23: 102: 28.36		ID3_HUMAN (38-97): 6.85e-20: 82.5: 36.67